ESCAPE-NET

European Sudden Cardiac Arrest network: toward Prevention, Education and New Treatment

1. To combine Europe’s largest deep-phenotyped sudden cardiac arrest cohorts for full exploitation of the data;
2. To identify genetic, epigenetic, acquired, and environmental risk factors, and their interactions, for sudden cardiac arrest occurrence in a combined large-scale European study population;
3. To develop and validate a personalized risk score for sudden cardiac arrest occurrence;
4. To relate differences in first-response sudden cardiac arrest treatment to survival across different  European countries;
5. To evaluate effects of novel technologies for sudden cardiac arrest treatment by utilizing smart phone applications (for rapid deployment of lay rescuers) and ICT solutions (waveform analysis);
6. To design a personalized risk score for survival after sudden cardiac arrest.

€9,992,881

The research group participates in this consortium and provides four cohorts: the Hoorn Study, The New Hoorn Study, the String of Pearls Initiative, and the Hoorn Diabetes Care System cohort. The research group is responsible for the development and validation of prediction models for occurrence of sudden cardiac arrest and survival after sudden cardiac arrest for use in clinical practice. Data used for model development will include variables on demographics, known cardiovascular risk factors, clinical data, medication use, ECG data, socio-economic and environmental data, DNA- genotype

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