Publicaties

2024

Remmelzwaal S, Yeung SMH, Blom MT, de Borst MH, Elders PJM, Beulens JWJ. Increased interleukin-6 is associated with higher risk of heart failure in people with type 2 diabetes. ESC Heart Fail. Published online March 28, 2024 Article

2023

Allesøe RL, Lundgaard AT, Hernández Medina R, Aguayo-Orozco A, Johansen J, Nissen JN, et al Discovery of drug–omics associations in type 2 diabetes with generative deep-learning models Nature Biotechnology 2023 Article

Allesøe RL, Lundgaard AT, Hernández Medina R, Aguayo-Orozco A, Johansen J, Nissen JN, et al Author Correction: Discovery of drug–omics associations in type 2 diabetes with generative deep-learning models (Nature Biotechnology, (2023), 41, 3, (399-408), 10.1038/s41587-022-01520-x) Nature Biotechnology 2023 Article

Bouman EJ, Beulens JWJ, den Braver NR, Blom MT, Remmelzwaal S, Elders PJM, Rutters F Social jet lag and (changes in) glycemic and metabolic control in people with type 2 diabetes Obesity (Silver Spring) 2023 Article

Dal Canto E, Elders PJM, van der Heijden AA, van Ballegooijen AJ, Lissenberg-Witte BI, Rutters F, Beulens JWJ Kidney function measures and cardiovascular outcomes in people with diabetes: the Hoorn Diabetes Care System cohort Diabetologia 2023 Article

de Klerk JA, Beulens JWJ, Mei H, Bijkerk R, van Zonneveld AJ, Koivula RW, et al Altered blood gene expression in the obesity-related type 2 diabetes cluster may be causally involved in lipid metabolism: a Mendelian randomisation study Diabetologia 2023 Article

Groeneveld L, den Braver NR, Beulens JWJ, van der Heijden AA, van der Reep AC, Remmelzwaal S, et al The prevalence of self-reported insomnia symptoms and association with metabolic outcomes in people with type 2 diabetes: the Hoorn Diabetes Care System cohort J Clin Sleep Med 2023 Article

Harms PP, Elders P, Rutters F, Lissenberg-Witte BI, Tan HL, Beulens JWJ, et al Longitudinal association of electrocardiogram abnormalities with major adverse cardiac events in people with Type 2 diabetes: the Hoorn Diabetes Care System cohort Eur J Prev Cardiol 2023 Article

Li X, Hoogenveen R, El Alili M, Knies S, Wang J, Beulens JWJ, et al Cost-Effectiveness of SGLT2 Inhibitors in a Real-World Population: A MICADO Model-Based Analysis Using Routine Data from a GP Registry Pharmacoeconomics 2023 Article

Li X, van Giessen A, Altunkaya J, Slieker RC, Beulens JWJ, t Hart LM, et al Potential Value of Identifying Type 2 Diabetes Subgroups for Guiding Intensive Treatment: A Comparison of Novel Data-Driven Clustering With Risk-Driven Subgroups Diabetes Care 2023 Article

Raadsen R, Agca R, Boers M, van Halm VP, Peters MJL, Smulders Y, et al In RA patients without prevalent CVD, incident CVD is mainly associated with traditional risk factors: A 20-year follow-up in the CARRÉ cohort study Semin Arthritis Rheum 2023 Article

Rotbain Curovic V, Tofte N, Lindhardt M, Adamova K, Bakker SJL, Beige J, et al Presence of retinopathy and incident kidney and cardiovascular events in type 2 diabetes with normoalbuminuria – A post-hoc analysis of the PRIORITY randomized clinical trial J Diabetes Complications 2023 Article

Tschiderer L, Seekircher L, Izzo R, Mancusi C, Manzi MV, Baldassarre D, et al Association of Intima-Media Thickness Measured at the Common Carotid Artery With Incident Carotid Plaque: Individual Participant Data Meta-Analysis of 20 Prospective Studies J Am Heart Assoc 2023 Article

Vreijling SR, van Haeringen M, Milaneschi Y, Huider F, Bot M, Amin N, et al Sociodemographic, lifestyle and clinical characteristics of energy-related depression symptoms: A pooled analysis of 13,965 depressed cases in 8 Dutch cohorts J Affect Disord 2023 Article

Welten S, Remmelzwaal S, Blom MT, van der Heijden AA, Nijpels G, Tan HL, et al Validation of the ARIC prediction model for sudden cardiac death in the European population: The ESCAPE-NET project Am Heart J 2023 Article

Welten, S. J. G. C., van der Heijden, A. A., Remmelzwaal, S., Blom, M. T., Nijpels, G., Rutters, F., Beulens, J. W. J., Elders, P. J. M., & ESCAPE-NET investigators  Prolongation of the QTc interval is associated with an increased risk of cardiovascular diseases: The Hoorn study 2023 Article

 

2022

Dal Canto E, Remmelzwaal S, van Ballegooijen AJ, Handoko ML, Heymans S, van Empel V, et al Diagnostic value of echocardiographic markers for diastolic dysfunction and heart failure with preserved ejection fraction Heart Fail Rev 2022 Article

Emamipour S, Pagano E, Di Cuonzo D, Konings SRA, van der Heijden AA, Elders P, et al The transferability and validity of a population-level simulation model for the economic evaluation of interventions in diabetes: the MICADO model Acta Diabetol 2022 Article

Hoek AG, van Oort S, Elders PJM, Beulens JWJ Causal Association of Cardiovascular Risk Factors and Lifestyle Behaviors With Peripheral Artery Disease: A Mendelian Randomization Approach J Am Heart Assoc 2022 Article

Kanoni S, Graham SE, Wang Y, Surakka I, Ramdas S, Zhu X, et al Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis Genome Biol 2022 Article

Li S, Dragan I, Fung CH, Kuznetsov D, Hansen MK, Beulens JWJ, et al Novel subgroups of type 2 diabetes based on multi-Omics profiling: an IMI-RHAPSODY Study 2022 Article

Overbeek JA, Swart KMA, van der Pal EYM, Blom MT, Beulens JWJ, Nijpels G, et al The DIAbetes MANagement and Treatment (DIAMANT) Cohort Clin Epidemiol 2022 Article

Ramdas S, Judd J, Graham SE, Kanoni S, Wang Y, Surakka I, et al A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids Am J Hum Genet 2022 Article

Siddiqui NZ, Beulens JWJ, van der Vliet N, den Braver NR, Elders PJM, Rutters F The longitudinal association between chronic stress and (visceral) obesity over seven years in the general population: The Hoorn Studies Int J Obes (Lond) 2022 Article

Slurink IAL, den Braver NR, Rutters F, Kupper N, Smeets T, Elders PJM, et al Dairy product consumption and incident prediabetes in Dutch middle-aged adults: the Hoorn Studies prospective cohort Eur J Nutr 2022 Article

Vermeulen EA, de Jong HBT, Blomjous AGA, Eelderink C, Hoekstra T, Elders PJM, et al Magnesium intake and vascular structure and function: the Hoorn Study Eur J Nutr 2022 Article

Warming PE, Ågesen FN, Lynge TH, Jabbari R, Smits RLA, van Valkengoed IGM, et al Harmonization of the definition of sudden cardiac death in longitudinal cohorts of the European Sudden Cardiac Arrest network – towards Prevention, Education, and New Effective Treatments (ESCAPE-NET) consortium Am Heart J 2022 Article

Wesolowska-Andersen A, Brorsson CA, Bizzotto R, Mari A, Tura A, Koivula R, et al Four groups of type 2 diabetes contribute to the etiological and clinical heterogeneity in newly diagnosed individuals: An IMI DIRECT study Cell Rep Med 2022 Article

Yang Z, Macdonald-Dunlop E, Chen J, Zhai R, Li T, Richmond A, et al Genetic Landscape of the ACE2 Coronavirus Receptor Circulation 2022 Article

Yengo L, Vedantam S, Marouli E, Sidorenko J, Bartell E, Sakaue S, et al A saturated map of common genetic variants associated with human height Nature 2022 Article

2021

Aarts I, Vriend C, Snoek A, van den End A, Blankers M, Beekman ATF, et al Neural correlates of treatment effect and prediction of treatment outcome in patients with PTSD and comorbid personality disorder: study design Borderline Personal Disord Emot Dysregul 2021 Article

Beulens JWJ, Dal Canto E, Stehouwer CDA, Rennenberg R, Elders PJM, van Ballegooijen AJ High vitamin K status is prospectively associated with decreased left ventricular mass in women: the Hoorn Study Nutr J 2021 Article

Beulens JWJ, Yauw JS, Elders PJM, Feenstra T, Herings R, Slieker RC, et al Prognostic models for predicting the risk of foot ulcer or amputation in people with type 2 diabetes: a systematic review and external validation study Diabetologia 2021 Article

Bizzotto R, Jennison C, Jones AG, Kurbasic A, Tura A, Kennedy G, et al Processes Underlying Glycemic Deterioration in Type 2 Diabetes: An IMI DIRECT Study Diabetes Care 2021 Article

Braver NRd, Rutters F, Wagtendonk AJ, Kok JG, Harms PP, Brug J, et al Neighborhood walkability, physical activity and changes in glycemic markers in people with type 2 diabetes: The Hoorn Diabetes Care System cohort Health Place 2021 Article

Brouwer A, van Raalte DH, Lamers F, Rutters F, Elders PJM, Van Someren EJW, et al Insulin resistance as a marker for the immune-metabolic subtype of depression J Affect Disord 2021 Article

Deshmukh HA, Madsen AL, Vinuela A, Have CT, Grarup N, Tura A, et al Genome-Wide Association Analysis of Pancreatic Beta-Cell Glucose Sensitivity J Clin Endocrinol Metab 2021 Article

Graham SE, Clarke SL, Wu KH, Kanoni S, Zajac GJM, Ramdas S, et al The power of genetic diversity in genome-wide association studies of lipids Nature 2021 Article

Harms PP, van der Heijden AA, Rutters F, Tan HL, Beulens JWJ, Nijpels G, Elders P Prevalence of ECG abnormalities in people with type 2 diabetes: The Hoorn Diabetes Care System cohort J Diabetes Complications 2021 Article

Hoek AG, Zwakenberg SR, Elders PJM, de Jong PA, Spiering W, Bartstra JW, et al An elevated ankle-brachial index is not a valid proxy for peripheral medial arterial calcification Atherosclerosis 2021 Article

Kocevska D, Lysen TS, Dotinga A, Koopman-Verhoeff ME, Luijk M, Antypa N, et al Sleep characteristics across the lifespan in 1.1 million people from the Netherlands, United Kingdom and United States: a systematic review and meta-analysis Nat Hum Behav 2021 Article

Kozakova M, Gastaldelli A, Morizzo C, Højlund K, Nilssson PM, Ferrannini E, et al Gamma-glutamyltransferase, arterial remodeling and prehypertension in a healthy population at low cardiometabolic risk Journal of Human Hypertension 2021 Article

Kremers SHM, Remmelzwaal S, Schalkwijk CG, Elders PJM, Stehouwer CDA, van Ballegooijen AJ, Beulens JWJ The role of serum and dietary advanced glycation endproducts in relation to cardiac function and structure: The Hoorn Study Nutr Metab Cardiovasc Dis 2021 Article

Memarian E, t Hart LM, Slieker RC, Lemmers RFL, van der Heijden AA, Rutters F, et al Plasma protein N-glycosylation is associated with cardiovascular disease, nephropathy, and retinopathy in type 2 diabetes BMJ Open Diabetes Res Care 2021 Article

Nijpels G, van der Heijden A, Elders P, Beulens JWJ, de Vet HCW The interobserver agreement of ECG abnormalities using Minnesota codes in people with type 2 diabetes PLoS One 2021 Article

Obura M, Beulens JWJ, Slieker R, Koopman ADM, Hoekstra T, Nijpels G, et al Clinical profiles of post-load glucose subgroups and their association with glycaemic traits over time: An IMI-DIRECT study Diabet Med 2021 Article

Pagano E, Konings SRA, Di Cuonzo D, Rosato R, Bruno G, van der Heijden AA, et al Prediction of mortality and major cardiovascular complications in type 2 diabetes: External validation of UK Prospective Diabetes Study outcomes model version 2 in two European observational cohorts Diabetes Obes Metab 2021 Article

Remmelzwaal S, Beulens JWJ, Elders PJM, Stehouwer CDA, Handoko ML, Appelman Y, et al Sex-specific associations of body composition measures with cardiac function and structure after 8 years of follow-up Sci Rep 2021 Article

Remmelzwaal S, Beulens JWJ, Elders PJM, Stehouwer CDA, Zhang Z, Handoko ML, et al Sex differences in the longitudinal relationship of low-grade inflammation and echocardiographic measures in the Hoorn and FLEMENGHO Study PLoS One 2021 Article

Slieker RC, Donnelly LA, Fitipaldi H, Bouland GA, Giordano GN, Åkerlund M, et al Distinct Molecular Signatures of Clinical Clusters in People With Type 2 Diabetes: An IMI-RHAPSODY Study Diabetes 2021 Article

Slieker RC, Donnelly LA, Fitipaldi H, Bouland GA, Giordano GN, Åkerlund M, et al Replication and cross-validation of type 2 diabetes subtypes based on clinical variables: an IMI-RHAPSODY study Diabetologia 2021 Article

Slieker RC, van der Heijden A, Siddiqui MK, Langendoen-Gort M, Nijpels G, Herings R, et al Performance of prediction models for nephropathy in people with type 2 diabetes: systematic review and external validation study Bmj 2021 Article

Tura A, Grespan E, Gobl CS, Koivula RW, Franks PW, Pearson ER, et al Profiles of Glucose Metabolism in Different Prediabetes Phenotypes, Classified by Fasting Glycemia, 2-Hour OGTT, Glycated Hemoglobin, and 1-Hour OGTT: An IMI DIRECT Study Diabetes 2021 Article

van Dongen LH, Harms PP, Hoogendoorn M, Zimmerman DS, Lodder EM, t Hart LM, et al Discovery of predictors of sudden cardiac arrest in diabetes: rationale and outline of the RESCUED (REcognition of Sudden Cardiac arrest vUlnErability in Diabetes) project Open Heart 2021 Article

van Oort S, Rutters F, Warlé-van Herwaarden MF, Schram MT, Stehouwer CD, Tack CJ, et al Characteristics associated with polypharmacy in people with type 2 diabetes: the Dutch Diabetes Pearl cohort Diabet Med 2021 Article

2020

Agca R, Hopman L, Laan KJC, van Halm VP, Peters MJL, Smulders YM, et al Cardiovascular Event Risk in Rheumatoid Arthritis Compared with Type 2 Diabetes: A 15-year Longitudinal Study J Rheumatol 2020 Article

Atabaki-Pasdar N, Ohlsson M, Vinuela A, Frau F, Pomares-Millan H, Haid M, et al Predicting and elucidating the etiology of fatty liver disease: A machine learning modeling and validation study in the IMI DIRECT cohorts PLoS Med 2020 Article

Bahls M, Lorenz MW, Dörr M, Gao L, Kitagawa K, Tuomainen TP, et al Progression of conventional cardiovascular risk factors and vascular disease risk in individuals: insights from the PROG-IMT consortium Eur J Prev Cardiol 2020 Article

Bar N, Korem T, Weissbrod O, Zeevi D, Rothschild D, Leviatan S, et al A reference map of potential determinants for the human serum metabolome Nature 2020 Article

Bot M, Milaneschi Y, Al-Shehri T, Amin N, Garmaeva S, Onderwater GLJ, et al Metabolomics Profile in Depression: A Pooled Analysis of 230 Metabolic Markers in 5283 Cases With Depression and 10,145 Controls Biol Psychiatry 2020 Article

Brouwer A, van Raalte DH, Rutters F, Elders PJM, Snoek FJ, Beekman ATF, Bremmer MA Sleep and HbA(1c) in Patients With Type 2 Diabetes: Which Sleep Characteristics Matter Most? Diabetes Care 2020 Article

Dal Canto E, Beulens JWJ, Elders P, Rutters F, Stehouwer CDA, van der Heijden AA, van Ballegooijen AJ The Association of Vitamin D and Vitamin K Status with Subclinical Measures of Cardiovascular Health and All-Cause Mortality in Older Adults: The Hoorn Study J Nutr 2020 Article

de Jong M, Oskam MJ, Sep SJS, Ozcan B, Rutters F, Sijbrands EJG, et al Sex differences in cardiometabolic risk factors, pharmacological treatment and risk factor control in type 2 diabetes: findings from the Dutch Diabetes Pearl cohort BMJ Open Diabetes Res Care 2020 Article

den Braver NR, Rutters F, van der Spek A, Ibi D, Looman M, Geelen A, et al Adherence to a food group-based dietary guideline and incidence of prediabetes and type 2 diabetes Eur J Nutr 2020 Article

Emamipour S, van der Heijden A, Nijpels G, Elders P, Beulens JWJ, Postma MJ, et al A personalised screening strategy for diabetic retinopathy: a cost-effectiveness perspective Diabetologia 2020 Article

Eriksen R, Perez IG, Posma JM, Haid M, Sharma S, Prehn C, et al Dietary metabolite profiling brings new insight into the relationship between nutrition and metabolic risk: An IMI DIRECT study EBioMedicine 2020 Article

Fedko IO, Hottenga JJ, Helmer Q, Mbarek H, Huider F, Amin N, et al Measurement and genetic architecture of lifetime depression in the Netherlands as assessed by LIDAS (Lifetime Depression Assessment Self-report) Psychol Med 2020 Article

Gudmundsdottir V, Pedersen HK, Mazzoni G, Allin KH, Artati A, Beulens JW, et al Whole blood co-expression modules associate with metabolic traits and type 2 diabetes: an IMI-DIRECT study Genome Med 2020 Article

Hagenbeek FA, Pool R, van Dongen J, Draisma HHM, Jan Hottenga J, Willemsen G, et al Heritability estimates for 361 blood metabolites across 40 genome-wide association studies Nature Communications 2020 Article

Hagenbeek FA, Pool R, van Dongen J, Draisma HM, Jan Hottenga J, Willemsen G, et al Author Correction: Heritability estimates for 361 blood metabolites across 40 genome-wide association studies (Nature Communications, (2020), 11, 1, (39), 10.1038/s41467-019-13770-6) Nature Communications 2020 Article

Koivula RW, Atabaki-Pasdar N, Giordano GN, White T, Adamski J, Bell JD, et al The role of physical activity in metabolic homeostasis before and after the onset of type 2 diabetes: an IMI DIRECT study Diabetologia 2020 Article

Lakerveld J, Wagtendonk A, Vaartjes I, Karssenberg D Deep phenotyping meets big data: the Geoscience and hEalth Cohort COnsortium (GECCO) data to enable exposome studies in The Netherlands Int J Health Geogr 2020 Article

Linssen PBC, Brunner-La Rocca HP, Schalkwijk CG, Beulens JWJ, Elders PJM, van der Heijden AA, et al Serum Matrix Metalloproteinases and Left Atrial Remodeling-The Hoorn Study Int J Mol Sci 2020 Article

Liu J, Lahousse L, Nivard MG, Bot M, Chen L, van Klinken JB, et al Integration of epidemiologic, pharmacologic, genetic and gut microbiome data in a drug-metabolite atlas Nat Med 2020 Article

Obura M, Beulens JWJ, Slieker R, Koopman ADM, Hoekstra T, Nijpels G, et al Post-load glucose subgroups and associated metabolic traits in individuals with type 2 diabetes: An IMI-DIRECT study PLoS One 2020 Article

Rutters F, Nijpels G, Elders P, Stehouwer CDA, van der Heijden AA, Groeneveld L, et al Corrigendum to: Cohort Profile: The Hoorn Studies Int J Epidemiol 2020 Article

Simons N, Bijnen M, Wouters KAM, Rensen SS, Beulens JWJ, van Greevenbroek MMJ, et al The endothelial function biomarker soluble E-selectin is associated with nonalcoholic fatty liver disease Liver Int 2020 Article

Singh SS, Naber A, Dotz V, Schoep E, Memarian E, Slieker RC, et al Metformin and statin use associate with plasma protein N-glycosylation in people with type 2 diabetes BMJ Open Diabetes Res Care 2020 Article

Tofte N, Lindhardt M, Adamova K, Bakker SJL, Beige J, Beulens JWJ, et al Early detection of diabetic kidney disease by urinary proteomics and subsequent intervention with spironolactone to delay progression (PRIORITY): a prospective observational study and embedded randomised placebo-controlled trial Lancet Diabetes Endocrinol 2020 Article

Tofte N, Vogelzangs N, Mook-Kanamori D, Brahimaj A, Nano J, Ahmadizar F, et al Plasma Metabolomics Identifies Markers of Impaired Renal Function: A Meta-analysis of 3089 Persons with Type 2 Diabetes J Clin Endocrinol Metab 2020 Article

van den Akker EB, Trompet S, Barkey Wolf JJH, Beekman M, Suchiman HED, Deelen J, et al Metabolic Age Based on the BBMRI-NL (1)H-NMR Metabolomics Repository as Biomarker of Age-related Disease Circ Genom Precis Med 2020 Article

van der Heijden AA, Nijpels G, Badloe F, Lovejoy HL, Peelen LM, Feenstra TL, et al Prediction models for development of retinopathy in people with type 2 diabetes: systematic review and external validation in a Dutch primary care setting Diabetologia 2020 Article

van Meijel LA, de Vegt F, Abbink EJ, Rutters F, Schram MT, van der Klauw MM, et al High prevalence of impaired awareness of hypoglycemia and severe hypoglycemia among people with insulin-treated type 2 diabetes: The Dutch Diabetes Pearl Cohort BMJ Open Diabetes Res Care 2020 Article

van Oort S, Beulens JW, van der Heijden A, Elders PJM, Stehouwer CDA, van de Luitgaarden IAT, et al Moderate and heavy alcohol consumption are prospectively associated with decreased left ventricular ejection fraction: The Hoorn Study Nutr Metab Cardiovasc Dis 2020 Article

van Puffelen A, Kasteleyn M, de Vries L, Rijken M, Heijmans M, Nijpels G, Schellevis F Self-care of patients with type 2 diabetes mellitus over the course of illness: implications for tailoring support J Diabetes Metab Disord 2020 Article

Wisgerhof W, Ruijgrok C, den Braver NR, Borgonjen-van den Berg KJ, van der Heijden A, Elders PJM, et al Phenotypic and lifestyle determinants of HbA1c in the general population-The Hoorn Study PLoS One 2020 Article

Zwakenberg SR, de Jong PA, Hendriks EJ, Westerink J, Spiering W, de Borst GJ, et al Intimal and medial calcification in relation to cardiovascular risk factors PLoS One 2020 Article

2019

Brouwer A, van Raalte DH, Nguyen HT, Rutters F, van de Ven PM, Elders PJM, et al Effects of Light Therapy on Mood and Insulin Sensitivity in Patients With Type 2 Diabetes and Depression: Results From a Randomized Placebo-Controlled Trial Diabetes Care 2019 Article

Dawed AY, Zhou K, van Leeuwen N, Mahajan A, Robertson N, Koivula R, et al Variation in the Plasma Membrane Monoamine Transporter (PMAT) (Encoded by SLC29A4) and Organic Cation Transporter 1 (OCT1) (Encoded by SLC22A1) and Gastrointestinal Intolerance to Metformin in Type 2 Diabetes: An IMI DIRECT Study Diabetes Care 2019 Article

Generaal E, Hoogendijk EO, Stam M, Henke CE, Rutters F, Oosterman M, et al Neighbourhood characteristics and prevalence and severity of depression: pooled analysis of eight Dutch cohort studies Br J Psychiatry 2019 Article

Grubb AL, McDonald TJ, Rutters F, Donnelly LA, Hattersley AT, Oram RA, et al A Type 1 Diabetes Genetic Risk Score Can Identify Patients With GAD65 Autoantibody-Positive Type 2 Diabetes Who Rapidly Progress to Insulin Therapy Diabetes Care 2019 Article

Koopman ADM, Beulens JW, van der Heijden A, Elders P, Dekker JM, Alssema M, Rutters F A prospective study on glucagon responses to oral glucose and mixed meal and 7-year change in fasting glucose Clin Endocrinol (Oxf) 2019 Article

Koopman ADM, Beulens JW, Voerman E, Rauh SP, van der Heijden AA, McDonald TJ, et al The association between GAD65 antibody levels and incident Type 2 Diabetes Mellitus in an adult population: A meta-analysis Metabolism 2019 Article

Overbeek JA, Kuiper JG, van der Heijden A, Labots M, Haug U, Herings RMC, Nijpels G Sex- and site-specific differences in colorectal cancer risk among people with type 2 diabetes Int J Colorectal Dis 2019 Article

Overbeek JA, van Herk-Sukel MPP, Vissers PAJ, van der Heijden A, Bronsveld HK, Herings RMC, et al Type 2 Diabetes, but Not Insulin (Analog) Treatment, Is Associated With More Advanced Stages of Breast Cancer: A National Linkage of Cancer and Pharmacy Registries Diabetes Care 2019 Article

Pennells L, Kaptoge S, Wood A, Sweeting M, Zhao X, White I, et al Equalization of four cardiovascular risk algorithms after systematic recalibration: individual-participant meta-analysis of 86 prospective studies Eur Heart J 2019 Article

Slieker RC, van der Heijden A, Nijpels G, Elders PJM, t Hart LM, Beulens JWJ Visit-to-visit variability of glycemia and vascular complications: the Hoorn Diabetes Care System cohort Cardiovasc Diabetol 2019 Article

van Dijk D, Balkau B, Segrestin B, Gottsäter M, Gabriel R, Hatunic M, et al Associations between sleep duration and sleep debt with insulin sensitivity and insulin secretion in the EGIR-RISC Study Diabetes Metab 2019 Article

van Puffelen AL, Heijmans MJ, Schellevis FG, Nijpels G, Rijken M Improving self-management of people with type 2 diabetes in the first years after diagnosis: Development and pilot of a theory-based interactive group intervention SAGE Open Med 2019 Article

van Puffelen AL, Rijken M, Heijmans M, Nijpels G, Schellevis FG Effectiveness of a self-management support program for type 2 diabetes patients in the first years of illness: Results from a randomized controlled trial PLoS One 2019 Article

Wilman HR, Parisinos CA, Atabaki-Pasdar N, Kelly M, Thomas EL, Neubauer S, et al Genetic studies of abdominal MRI data identify genes regulating hepcidin as major determinants of liver iron concentration J Hepatol 2019 Article

2018

Allin KH, Tremaroli V, Caesar R, Jensen BAH, Damgaard MTF, Bahl MI, et al Aberrant intestinal microbiota in individuals with prediabetes Diabetologia 2018 Article

de Las Heras Gala T, Herder C, Rutters F, Carstensen-Kirberg M, Huth C, Stehouwer CDA, et al Association of changes in inflammation with variation in glycaemia, insulin resistance and secretion based on the KORA study Diabetes Metab Res Rev 2018 Article

Empana JP, Blom MT, Bӧttiger BW, Dagres N, Dekker JM, Gislason G, et al Determinants of occurrence and survival after sudden cardiac arrest-A European perspective: The ESCAPE-NET project Resuscitation 2018 Article

Hulman A, Witte DR, Vistisen D, Balkau B, Dekker JM, Herder C, et al Pathophysiological Characteristics Underlying Different Glucose Response Curves: A Latent Class Trajectory Analysis From the Prospective EGIR-RISC Study Diabetes Care 2018 Article

Koopman ADM, Rutters F, Rauh SP, Nijpels G, Holst JJ, Beulens JW, et al Incretin responses to oral glucose and mixed meal tests and changes in fasting glucose levels during 7 years of follow-up: The Hoorn Meal Study PLoS One 2018 Article

Koopman ADM, Vd Ven M, Beulens JW, Welschen LM, Elders PJ, Nijpels G, Rutters F The Association between Eating Traits and Weight Change after a Lifestyle Intervention in People with Type 2 Diabetes Mellitus J Diabetes Res 2018 Article

Lorenz MW, Gao L, Ziegelbauer K, Norata GD, Empana JP, Schmidtmann I, et al Correction: Predictive value for cardiovascular events of common carotid intima media thickness and its rate of change in individuals at high cardiovascular risk – Results from the PROG-IMT collaboration PLoS One 2018 Article

Lorenz MW, Gao L, Ziegelbauer K, Norata GD, Empana JP, Schmidtmann I, et al Predictive value for cardiovascular events of common carotid intima media thickness and its rate of change in individuals at high cardiovascular risk – Results from the PROG-IMT collaboration PLoS One 2018 Article

Özcan B, Rutters F, Snoek FJ, Roosendaal M, Sijbrands EJ, Elders PJM, et al High Diabetes Distress Among Ethnic Minorities Is Not Explained by Metabolic, Cardiovascular, or Lifestyle Factors: Findings From the Dutch Diabetes Pearl Cohort Diabetes Care 2018 Article

Rauh SP, Rutters F, van der Heijden A, Luimes T, Alssema M, Heymans MW, et al External Validation of a Tool Predicting 7-Year Risk of Developing Cardiovascular Disease, Type 2 Diabetes or Chronic Kidney Disease J Gen Intern Med 2018 Article

Ruijgrok C, Dekker JM, Beulens JW, Brouwer IA, Coupé VMH, Heymans MW, et al Size and shape of the associations of glucose, HbA(1c), insulin and HOMA-IR with incident type 2 diabetes: the Hoorn Study Diabetologia 2018 Article

Rutters F, Nijpels G, Elders P, Stehouwer CDA, van der Heijden AA, Groeneveld L, et al Cohort Profile: The Hoorn Studies Int J Epidemiol 2018 Article

Sedaghat S, van Sloten TT, Laurent S, London GM, Pannier B, Kavousi M, et al Common Carotid Artery Diameter and Risk of Cardiovascular Events and Mortality: Pooled Analyses of Four Cohort Studies Hypertension 2018 Article

Siméon S, Massy Z, Højlund K, Lalic K, Porcellati F, Dekker J, et al Renal function markers and insulin sensitivity after 3 years in a healthy cohort, the EGIR-RISC study BMC Nephrol 2018 Article

Slieker RC, van der Heijden A, van Leeuwen N, Mei H, Nijpels G, Beulens JWJ, t Hart LM HbA(1c) is associated with altered expression in blood of cell cycle- and immune response-related genes Diabetologia 2018 Article

t Hart LM, Vogelzangs N, Mook-Kanamori DO, Brahimaj A, Nano J, van der Heijden A, et al Blood Metabolomic Measures Associate With Present and Future Glycemic Control in Type 2 Diabetes J Clin Endocrinol Metab 2018 Article

Timmermans EJ, Lakerveld J, Beulens JWJ, Boomsma DI, Kramer SE, Oosterman M, et al Cohort profile: the Geoscience and Health Cohort Consortium (GECCO) in the Netherlands BMJ Open 2018 Article

Tofte N, Lindhardt M, Adamova K, Beige J, Beulens JWJ, Birkenfeld AL, et al Characteristics of high- and low-risk individuals in the PRIORITY study: urinary proteomics and mineralocorticoid receptor antagonism for prevention of diabetic nephropathy in Type 2 diabetes Diabet Med 2018 Article

van Bussel BCT, Henry RMA, Schalkwijk CG, Dekker JM, Nijpels G, Feskens EJM, Stehouwer CDA Alcohol and red wine consumption, but not fruit, vegetables, fish or dairy products, are associated with less endothelial dysfunction and less low-grade inflammation: the Hoorn Study Eur J Nutr 2018 Article

van der Heijden AA, Abramoff MD, Verbraak F, van Hecke MV, Liem A, Nijpels G Validation of automated screening for referable diabetic retinopathy with the IDx-DR device in the Hoorn Diabetes Care System Acta Ophthalmol 2018 Article

van der Pal KC, Koopman ADM, Lakerveld J, van der Heijden AA, Elders PJ, Beulens JW, Rutters F The association between multiple sleep-related characteristics and the metabolic syndrome in the general population: the New Hoorn study Sleep Med 2018 Article

Wanders AJ, Alssema M, De Hoon SEM, Feskens EJM, van Woudenbergh GJ, van der Kallen CJ, et al Circulating Polyunsaturated Fatty Acids as Biomarkers for Dietary Intake across Subgroups: The CODAM and Hoorn Studies Ann Nutr Metab 2018 Article

2017

Bijlsma-Rutte A, Braamse AMJ, van Oppen P, et al. Screening for sexual dissatisfaction among people with type 2 diabetes in primary care J Diabetes Complications 2017 Article

Britton AR, Grobbee DE, den Ruijter HM, et al. Alcohol Consumption and Common Carotid Intima-Media Thickness: The USE-IMT Study Alcohol Alcohol 2017 Article

Cabout M, Alssema M, Nijpels G, et al. Circulating linoleic acid and alpha-linolenic acid and glucose metabolism: the Hoorn Study Eur J Nutr 2017 Article

Gaksch M, Jorde R, Grimnes G, et al. Vitamin D and mortality: Individual participant data meta-analysis of standardized 25-hydroxyvitamin D in 26916 individuals from a European consortium PLoS One 2017 Article

Gottsäter M, Balkau B, Hatunic M, et al. Insulin resistance and β-cell function in smokers: results from the EGIR-RISC European multicentre study Diabet Med 2017 Article

Hulman A, Simmons RK, Vistisen D, et al. Heterogeneity in glucose response curves during an oral glucose tolerance test and associated cardiometabolic risk Endocrine 2017 Article

Koopman ADM, Rauh SP, van ’t Riet E, et al. The Association between Social Jetlag, the Metabolic Syndrome, and Type 2 Diabetes Mellitus in the General Population: The New Hoorn Study J Biol Rhythms 2017 Article

Mast R, Rauh SP, Groeneveld L, et al. The Use of Antidepressants, Anxiolytics, and Hypnotics in People with Type 2 Diabetes and Patterns Associated with Use: The Hoorn Diabetes Care System Cohort Biomed Res Int 2017 Article

Overbeek JA, van der Heijden AW, Herings RM, et al. [Prevalence of diabetes mellitus in the Netherlands more than doubled in the period 1999-2014] Ned Tijdschr Geneeskd 2017 Article

Preiss D, Dawed A, Welsh P, et al. Sustained influence of metformin therapy on circulating glucagon-like peptide-1 levels in individuals with and without type 2 diabetes Diabetes Obes Metab 2017 Article

Rauh SP, Heymans MW, Koopman AD, Nijpels G, Stehouwer CD, Thorand B, et al Predicting glycated hemoglobin levels in the non-diabetic general population: Development and validation of the DIRECT-DETECT prediction model – a DIRECT study PLoS One 2017 Article

Rutte A, Rauh SP, Schram MT, et al. Individual and partner’s level of occupation and the association with HbA(1c) levels in people with Type 2 diabetes mellitus: the Dutch Diabetes Pearl cohort Diabet Med 2017 Article

van der Heijden AA, Rauh SP, Dekker JM, et al. The Hoorn Diabetes Care System (DCS) cohort. A prospective cohort of persons with type 2 diabetes treated in primary care in the Netherlands BMJ Open 2017 Article

van Moorsel D, Henry RM, Schaper NC, et al. BclI Glucocorticoid Receptor Polymorphism in Relation to Arterial Stiffening and Cardiac Structure and Function: The Hoorn and CODAM Studies Am J Hypertens 2017 Article

van Sloten TT Vascular dysfunction: At the heart of cardiovascular disease, cognitive impairment and depressive symptoms Artery Research 2017 Article

Wang X, Dalmeijer GW, den Ruijter HM, Anderson TJ, Britton AR, Dekker J, et al Clustering of cardiovascular risk factors and carotid intima-media thickness: The USE-IMT study PLoS One 2017 Article

Westra S, Simsek S, Rutters F, Krul-Poel YM, Stehouwer CD, Dekker JM, Pouwer F Low vitamin D levels are not a contributing factor to higher prevalence of depressive symptoms in people with Type 2 diabetes mellitus: the Hoorn study Diabet Med 2017 Article

Wood AR, Jonsson A, Jackson AU, Wang N, van Leewen N, Palmer ND, et al A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants Diabetes 2017 Article

2016

Bot SD, Mackenbach JD, Nijpels G, et al. Association between Social Network Characteristics and Lifestyle Behaviours in Adults at Risk of Diabetes and Cardiovascular Disease PLoS One 2016 Article

Cashman KD, Dowling KG, Škrabáková Z, et al. Vitamin D deficiency in Europe: pandemic? Am J Clin Nutr 2016 Article

Liao X, Norata GD, Polak JF, et al. Normative values for carotid intima media thickness and its progression: Are they transferrable outside of their cohort of origin? Eur J Prev Cardiol 2016 Article

Linssen PB, Henry RM, Schalkwijk CG, et al. Serum advanced glycation endproducts are associated with left ventricular dysfunction in normal glucose metabolism but not in type 2 diabetes: The Hoorn Study Diab Vasc Dis Res 2016 Article

Malanda UL, Bot SD, Kostense PJ, et al. Effects of self-monitoring of glucose on distress and self-efficacy in people with non-insulin-treated Type 2 diabetes: a randomized controlled trial Diabet Med 2016 Article

Mast MR, Walraven I, Hoekstra T, et al. Effectiveness of insulin therapy in people with Type 2 diabetes in the Hoorn Diabetes Care System Diabet Med 2016 Article

Mast R, Danielle Jansen AP, Walraven I, et al. Time to insulin initiation and long-term effects of initiating insulin in people with type 2 diabetes mellitus: the Hoorn Diabetes Care System Cohort Study Eur J Endocrinol 2016 Article

Rauh SP, Rutters F, Thorsted BL, et al. Self-reported hypoglycaemia in patients with type 2 diabetes treated with insulin in the Hoorn Diabetes Care System Cohort, the Netherlands: a prospective cohort study BMJ Open 2016 Article

Rutte A, Welschen LM, van Splunter MM, et al. Type 2 Diabetes Patients’ Needs and Preferences for Care Concerning Sexual Problems: A Cross-Sectional Survey and Qualitative Interviews J Sex Marital Ther 2016 Article

Rutters F, Besson H, Walker M, et al. The Association Between Sleep Duration, Insulin Sensitivity, and β-Cell Function: The EGIR-RISC Study J Clin Endocrinol Metab 2016 Article

Simons N, Dekker JM, van Greevenbroek MM, et al. A Common Gene Variant in Glucokinase Regulatory Protein Interacts With Glucose Metabolism on Diabetic Dyslipidemia: the Combined CODAM and Hoorn Studies Diabetes Care 2016 Article

Wanders AJ, Alssema M, van Greevenbroek MJ, et al. Comment on Sergeant et al. : Impact of methods used to express levels of circulating fatty acids on the degree and direction of associations with blood lipids in humans Br J Nutr 2016 Article

Willeit P, Thompson SG, Agewall S, et al. Inflammatory markers and extent and progression of early atherosclerosis: Meta-analysis of individual-participant-data from 20 prospective studies of the PROG-IMT collaboration Eur J Prev Cardiol 2016 Article

Zhou K, Yee SW, Seiser EL, et al. Variation in the glucose transporter gene SLC2A2 is associated with glycemic response to metformin Nat Genet 2016 Article

2015

Bonnet F, Empana JP, Natali A, et al. Elevated heart rate predicts β cell function in non-diabetic individuals: the RISC cohort Eur J Endocrinol 2015 Article

Brouwer A, van Raalte DH, Diamant M, et al. Light therapy for better mood and insulin sensitivity in patients with major depression and type 2 diabetes: a randomised, double-blind, parallel-arm trial BMC Psychiatry 2015 Article 

Di Angelantonio E, Kaptoge S, Wormser D, et al. Association of Cardiometabolic Multimorbidity With Mortality Jama 2015 Article

Eikendal AL, Groenewegen KA, Anderson TJ, et al. Common carotid intima-media thickness relates to cardiovascular events in adults aged <45 years Hypertension 2015 Article

Gaens KH, Ferreira I, van de Waarenburg MP, et al. Protein-Bound Plasma Nε-(Carboxymethyl)lysine Is Inversely Associated With Central Obesity and Inflammation and Significantly Explain a Part of the Central Obesity-Related Increase in Inflammation: The Hoorn and CODAM Studies Arterioscler Thromb Vasc Biol 2015 Article

Gijsberts CM, Groenewegen KA, Hoefer IE, et al. Race/Ethnic Differences in the Associations of the Framingham Risk Factors with Carotid IMT and Cardiovascular Events PLoS One 2015 Article

Kasteleyn MJ, de Vries L, van Puffelen AL, et al. Diabetes-related distress over the course of illness: Results from the Diacourse study Diabetic Medicine 2015 Article

Kozakova M, Palombo C, Morizzo C, et al. Obesity and carotid artery remodeling Nutrition and Diabetes 2015 Article

Lemmens LC, de Bruin SR, Struijs JN, et al. Patient involvement in diabetes care: experiences in nine diabetes care groups Int J Integr Care 2015 Article

Lorenz MW, Price JF, Robertson C, et al. Carotid intima-media thickness progression and risk of vascular events in people with diabetes: results from the PROG-IMT collaboration Diabetes Care 2015 Article

Pilz S, Rutters F, Nijpels G, et al. Response to Comment on Pilz et al. Insulin sensitivity and albuminuria: the RISC study. Diabetes Care 2014;37:1597-1603Diabetes Care 2015 Article

Protogerou AD, van Sloten TT, Henry RMA, et al. Pulse pressure measured at the level of the femoral artery, but not at the level of the aorta, carotid and brachial arteries, is associated with the incidence of coronary heart disease events in a population with a high prevalence of type 2 diabetes and impaired glucose metabolism – The Hoorn study Artery Research 2015 Article

Rutte A, van Oppen P, Nijpels G, et al. Effectiveness of a PLISSIT model intervention in patients with type 2 diabetes mellitus in primary care: design of a cluster-randomised controlled trial BMC Fam Pract 2015 Article

Rutte A, van Splunter MM, van der Heijden AA, et al. Prevalence and Correlates of Sexual Dysfunction in Men and Women With Type 2 Diabetes J Sex Marital Ther 2015 Article

Rutters F, Pilz S, Koopman AD, et al. Stressful life events and incident metabolic syndrome: the Hoorn study Stress 2015 Article

Teunissen CE, van der Flier WM, Scheltens P, et al. Serum leptin is not altered nor related to cognitive decline in Alzheimer’s disease J Alzheimers Dis 2015 Article

van Moorsel D, van Greevenbroek MM, Schaper NC, et al. BclI glucocorticoid receptor polymorphism in relation to cardiovascular variables: the Hoorn and CODAM studies Eur J Endocrinol 2015 Article

van Puffelen AL, Heijmans MJ, Rijken M, et al. Illness perceptions and self-care behaviours in the first years of living with type 2 diabetes; does the presence of complications matter? Psychol Health 2015 Article

Walraven I, Mast MR, Hoekstra T, et al. Real-world evidence of suboptimal blood pressure control in patients with type 2 diabetes J Hypertens 2015 Article

Walraven I, Mast MR, Hoekstra T, et al. Distinct HbA1c trajectories in a type 2 diabetes cohort Acta Diabetol 2015 Article

Wilgenhof S, Corthals J, Van Nuffel AMT, et al. Long-term clinical outcome of melanoma patients treated with messenger RNA-electroporated dendritic cell therapy following complete resection of metastases Cancer Immunology, Immunotherapy 2015 Article

2014

Abbass AA, Kisely SR, Town JM, et al. Short-term psychodynamic psychotherapies for common mental disorders Cochrane Database of Systematic Reviews 2014 Article

Altenburg TM, Lakerveld J, Bot SD, et al. The prospective relationship between sedentary time and cardiometabolic health in adults at increased cardiometabolic risk – the Hoorn Prevention Study International Journal of Behavioral Nutrition and Physical Activity 2014 Article

Beijers HJ, Ferreira I, Bravenboer B, et al. Higher central fat mass and lower peripheral lean mass are independent determinants of endothelial dysfunction in the elderly: the Hoorn study Atherosclerosis 2014 Article

Bots ML, Groenewegen KA, Anderson TJ, et al. Common carotid intima-media thickness measurements do not improve cardiovascular risk prediction in individuals with elevated blood pressure: the USE-IMT collaboration Hypertension 2014 Article

Contardo Ayala AM, Nijpels G, Lakerveld J Validity of self-measured waist circumference in adults at risk of type 2 diabetes and cardiovascular disease BMC Medicine 2014 Article

de Vries L, van der Heijden AA, van ’t Riet E, et al. Peer support to decrease diabetes-related distress in patients with type 2 diabetes mellitus: design of a randomised controlled trial BMC Endocr Disord 2014 Article

Di Angelantonio E, Gao P, Khan H, et al. Glycated hemoglobin measurement and prediction of cardiovascular disease Jama 2014 Article

Fowkes FGR, Murray GD, Butcher I, et al. Development and validation of an ankle brachial index risk model for the prediction of cardiovascular events European Journal of Preventive Cardiology 2014 Article

Gijsberts CM, Groenewegen KA, Hoefer IE, et al. Ethnic differences in the effect of the Framingham risk factors on atherosclerosis and cardiovascular events in the USE-IMT cohort European Heart Journal 2014 

Guigas B, de Leeuw van Weenen JE, van Leeuwen N, et al. Sex-specific effects of naturally occurring variants in the dopamine receptor D2 locus on insulin secretion and Type 2 diabetes susceptibility Diabetic Medicine 2014 Article

Herbert A, Cruickshank JK, Laurent S, et al. Establishing reference values for central blood pressure and its amplification in a general healthy population and according to cardiovascular risk factors European Heart Journal 2014 Article

Heringa SM, van den Berg E, Reijmer YD, et al. Markers of low-grade inflammation and endothelial dysfunction are related to reduced information processing speed and executive functioning in an older population – the Hoorn Study Psychoneuroendocrinology 2014 Article

Heringa SM, Walraven I, Moll AC, et al. Vascular retinopathy in relation to cognitive functioning in an older population–the Hoorn Study J Am Geriatr Soc 2014 Article

Hillebrand S, de Mutsert R, den Heijer M, et al. Autonomic function is not associated with the incidence of type 2 diabetes in a high-risk population: the Hoorn study Diabetes Metab 2014 Article

Koivula RW, Heggie A, Barnett A, et al. Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: Rationale and design of the epidemiological studies within the IMI DIRECT Consortium Diabetologia 2014 Article

Lakerveld J, Bot S, Nijpels G The effectiveness of lifestyle interventions in primary care Huisarts en Wetenschap 2014 

Pilz S, Rutters F, Nijpels G, et al. Insulin sensitivity and albuminuria: the RISC study Diabetes Care 2014 Article

Pilz S, Teerlink T, Scheffer PG, et al. Homoarginine and mortality in an older population: the Hoorn study Eur J Clin Invest 2014 Article

Rutters F, Pilz S, Koopman AD, et al. The association between psychosocial stress and mortality is mediated by lifestyle and chronic diseases: the Hoorn Study Soc Sci Med 2014 Article

Scott RA, Fall T, Pasko D, et al. Common genetic variants highlight the role of insulin resistance and body fat distribution in type 2 diabetes, independent of obesity Diabetes 2014 Article

Soulimane S, Simon D, Herman WH, et al. HbA1c, fasting and 2 h plasma glucose in current, ex- and never-smokers: A meta-analysis Diabetologia 2014 Article

van der Heijden AA, Walraven I, van ’t Riet E, et al. Validation of a model to estimate personalised screening frequency to monitor diabetic retinopathy Diabetologia 2014 Article

van der Pols-Vijlbrief R, Dekker JM, Stehouwer CD, et al. Symptom burden and its association with change in glucose metabolism status over a 7-year period: the Hoorn Study Diabet Med 2014 Article

van Sloten TT, Henry RM, Dekker JM, et al. Endothelial dysfunction plays a key role in increasing cardiovascular risk in type 2 diabetes: the Hoorn study Hypertension 2014 Article

van Sloten TT, Schram MT, Adriaanse MC, et al. Endothelial dysfunction is associated with a greater depressive symptom score in a general elderly population: the Hoorn Study Psychol Med 2014 Article

van Sloten TT, Schram MT, van den Hurk K, et al. Local stiffness of the carotid and femoral artery is associated with incident cardiovascular events and all-cause mortality: the Hoorn study J Am Coll Cardiol 2014 Article

Walraven I, van den Hurk K, van ’t Riet E, et al. Low-grade inflammation and endothelial dysfunction explain the association between retinopathy and left ventricular ejection fraction in men: an 8-year follow-up of the Hoorn Study J Diabetes Complications 2014 Article

2013

Adhien P, van Dijk L, de Vegter M, et al. Evaluation of a pilot study to influence medication adherence of patients with diabetes mellitus type-2 by the pharmacy Int J Clin Pharm 2013 Article

Alayli-Goebbels AFG, Dellaert BGC, Knox SA, et al. Consumer preferences for health and nonhealth outcomes of health promotion: Results from a discrete choice experiment Value in Health 2013 Article

Albrechtsen A, Grarup N, Li Y, Sparsø T, et al. Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes Diabetologia 2013 Article

Alssema M, Rijkelijkhuizen JM, Holst JJ, et al. Preserved GLP-1 and exaggerated GIP secretion in type 2 diabetes and relationships with triglycerides and ALT Eur J Endocrinol 2013 Article

Bot M, Pouwer F, De Jonge P, et al. Depressive symptoms, insulin sensitivity and insulin secretion in the RISC cohort study Diabetes and Metabolism 2013 Article

den Ruijter HM, Peters SA, Groenewegen KA, et al. Common carotid intima-media thickness does not add to Framingham risk score in individuals with diabetes mellitus: the USE-IMT initiative Diabetologia 2013 Article

Diener HC, Nitschmann S [Intima-media thickness of the carotid artery as a cardiovascular predictor. Progression Intima-Media Thickness (PROG-IMT)] Internist (Berl) 2013 Article

Elliott HR, Walia GK, Duggirala A, et al. Migration and DNA methylation: a comparison of methylation patterns in type 2 diabetes susceptibility genes between indians and europeans J Diabetes Res Clin Metab 2013 Article

Elshorbagy AK, Nijpels G, Valdivia-Garcia M, et al. S-adenosylmethionine is associated with fat mass and truncal adiposity in older adults Journal of Nutrition 2013 Article

Geelen CC, van Greevenbroek MM, van Rossum EF, et al. BclI glucocorticoid receptor polymorphism is associated with greater body fatness: the Hoorn and CODAM studies J Clin Endocrinol Metab 2013 Article

Hanssen NMJ, Engelen L, Ferreira I, et al. Plasma levels of advanced glycation endproducts Nε-(carboxymethyl) lysine, Nε-(carboxyethyl)lysine, and pentosidine are not independently associated with cardiovascular disease in individuals with or without type 2 diabetes: The hoorn and CODAM studies Journal of Clinical Endocrinology and Metabolism 2013 Article

Hanssen NMJ, Huijberts MS, Schalkwijk CG, et al. Response to Comment on: Hanssen et al. Associations between the ankle- brachial index and cardiovascular and all-cause mortality are similar in individuals without and with type 2 diabetes: Nineteen- year follow-up of a population-based cohort study. Diabetes Care 2012;35:1731-1735 Diabetes Care 2013 Article

Koekkoek PS, Rutten GEHM, Ruis C, et al. Mild depressive symptoms do not influence cognitive functioning in patients with type 2 diabetes Psychoneuroendocrinology 2013 Article

Kozakova M, Natali A, Dekker J, et al. Insulin sensitivity and carotid intima-media thickness: Relationship between insulin sensitivity and cardiovascular risk study Arteriosclerosis, Thrombosis, and Vascular Biology 2013 Article

Kozàkovà M, Palombo C, Morizzo C, et al. Gender-specific differences in carotid intima-media thickness and its progression over three years: A multicenter European study Nutrition, Metabolism and Cardiovascular Diseases 2013 Article

Lahjibi E, Heude B, Dekker JM, et al. Impact of objectively measured sedentary behaviour on changes in insulin resistance and secretion over 3years in the RISC study: Interaction with weight gain Diabetes and Metabolism 2013 Article

Lakerveld J, Bot SD, Chinapaw MJ, et al. Motivational interviewing and problem solving treatment to reduce type 2 diabetes and cardiovascular disease risk in real life: a randomized controlled trial Int J Behav Nutr Phys Act 2013 Article

Lakerveld J, Bot SD, van der Ploeg HP, et al. The effects of a lifestyle intervention on leisure-time sedentary behaviors in adults at risk: the Hoorn Prevention Study, a randomized controlled trial Prev Med 2013 Article

Luttmer R, Spijkerman AM, Kok RM, et al. Metabolic syndrome components are associated with DNA hypomethylation Obes Res Clin Pract 2013 Article

Malanda UL, Bot SD, Nijpels G Self-monitoring of blood glucose in noninsulin-using type 2 diabetic patients: It is time to face the evidence Diabetes Care 2013 Article

Reinders I, van Ballegooijen AJ, Visser M, et al. Associations of serum n-3 and n-6 polyunsaturated fatty acids with echocardiographic measures among older adults: the Hoorn Study Eur J Clin Nutr 2013 Article

van Aerde MA, Soedamah-Muthu SS, Geleijnse JM, et al. Dairy intake in relation to cardiovascular disease mortality and all-cause mortality: the Hoorn Study Eur J Nutr 2013 Article

van Ballegooijen AJ, Reinders I, Visser M, et al. Serum parathyroid hormone in relation to all-cause and cardiovascular mortality: the Hoorn study J Clin Endocrinol Metab 2013 Article

van der Heijden AA, Van’t Riet E, Bot SD, et al. Risk of a recurrent cardiovascular event in individuals with type 2 diabetes or intermediate hyperglycemia: the Hoorn Study Diabetes Care 2013 Article

van der Zwan LP, Davids M, Scheffer PG, et al. L-Homoarginine and L-arginine are antagonistically related to blood pressure in an elderly population: the Hoorn study J Hypertens 2013 Article

van Woudenbergh GJ, Theofylaktopoulou D, Kuijsten A, et al. Adapted dietary inflammatory index and its association with a summary score for low-grade inflammation and markers of glucose metabolism: the Cohort study on Diabetes and Atherosclerosis Maastricht (CODAM) and the Hoorn study Am J Clin Nutr 2013 Article

Vinknes KJ, Dekker JM, Drevon CA, et al. Plasma sulfur amino acids and stearoyl-CoA desaturase activity in two Caucasian populations Prostaglandins Leukot Essent Fatty Acids 2013 Article

Walraven I, van ’t Riet E, Stehouwer CD, et al. Fasting proinsulin levels are significantly associated with 20 year cancer mortality rates. The Hoorn Study Diabetologia 2013 Article

Welschen LM, van Oppen P, Bot SD, et al. Effects of a cognitive behavioural treatment in patients with type 2 diabetes when added to managed care; a randomised controlled trial J Behav Med 2013 Article

Xie W, Wood AR, Lyssenko V, et al. Genetic variants associated with glycine metabolism and their role in insulin sensitivity and type 2 diabetes Diabetes 2013 Article

2012

Matthias WL, Joseph FP, Maryam K, et al. Erratum: Carotid intima-media thickness progression to predict cardiovascular events in the general population (the PROG-IMT collaborative project): a meta-analysis of individual participant data (The Lancet (2012) 379(9831) (2053–2062) (S0140673612604413) 1016/S0140-6736(12)60441-3)) The Lancet 2012 Article 

Adhien P, Van Dijk L, Vegter M, et al. Tailored intervention for non-adherent diabetes patients; qualitative investigation of the feasibility of the intervention Pharmaceutisch Weekblad 2012 

Alssema M, Newson RS, Bakker SJ, et al. One risk assessment tool for cardiovascular disease, type 2 diabetes, and chronic kidney disease Diabetes Care 2012 Article

Beijers HJ, Ferreira I, Spronk HM, et al. Impaired glucose metabolism and type 2 diabetes are associated with hypercoagulability: potential role of central adiposity and low-grade inflammation–the Hoorn Study Thromb Res 2012 Article

Bunck MC, Poelma M, Eekhoff EM, et al. Effects of vildagliptin on postprandial markers of bone resorption and calcium homeostasis in recently diagnosed, well-controlled type 2 diabetes patients J Diabetes 2012 Article

de Hollander EL, Bemelmans WJ, Boshuizen HC, et al. The association between waist circumference and risk of mortality considering body mass index in 65- to 74-year-olds: A meta-analysis of 29 cohorts involving more than 58 000 elderly persons International Journal of Epidemiology 2012 Article

Handberg A, Højlund K, Gastaldelli A, et al. Plasma sCD36 is associated with markers of atherosclerosis, insulin resistance and fatty liver in a nondiabetic healthy population Journal of Internal Medicine 2012 Article

Hanssen NM, Huijberts MS, Schalkwijk CG, et al. Associations between the ankle-brachial index and cardiovascular and all-cause mortality are similar in individuals without and with type 2 diabetes: nineteen-year follow-up of a population-based cohort study Diabetes Care 2012 Article

Kozakova M, Palombo C, Paterni Eng M, et al. Fatty liver index, gamma-glutamyltransferase, and early carotid plaques Hepatology 2012 Article

Kroon MH, van den Hurk K, Alssema M, et al. Prospective associations of B-type natriuretic peptide with markers of left ventricular function in individuals with and without type 2 diabetes: an 8-year follow-up of the Hoorn Study Diabetes Care 2012 Article

Lakerveld J, Bot S, Chinapaw M, et al. Process evaluation of a lifestyle intervention to prevent diabetes and cardiovascular diseases in primary care Health Promot Pract 2012 Article

Lamberts EJF, Nijpels G, Welschen LMC, et al. Discontinuation of statins among patients with type 2 diabetes Diabetes/Metabolism Research and Reviews 2012 Article

Lorenz MW, Polak JF, Kavousi M, et al. Carotid intima-media thickness progression to predict cardiovascular events in the general population (the PROG-IMT collaborative project): a meta-analysis of individual participant data Lancet 2012 Article

Pilz S, van den Hurk K, Nijpels G, et al. Vitamin D status, incident diabetes and prospective changes in glucose metabolism in older subjects: the Hoorn study Nutr Metab Cardiovasc Dis 2012 Article

Reijmer YD, van den Berg E, Dekker JM, et al. Development of vascular risk factors over 15 years in relation to cognition: the Hoorn Study J Am Geriatr Soc 2012 Article

Song X, Pitkäniemi J, Gao W, et al. Relationship between body mass index and mortality among Europeans European Journal of Clinical Nutrition 2012 Article

van ’t Riet E, Rijkelijkhuizen JM, Alssema M, et al. HbA1c is an independent predictor of non-fatal cardiovascular disease in a Caucasian population without diabetes: a 10-year follow-up of the Hoorn Study Eur J Prev Cardiol 2012 Article

van Ballegooijen AJ, Snijder MB, Visser M, et al. Vitamin D in relation to myocardial structure and function after eight years of follow-up: the Hoorn study Ann Nutr Metab 2012 Article

van Ballegooijen AJ, Visser M, Snijder MB, et al. Serum 25-hydroxyvitamin D and parathyroid hormone in relation to plasma B-type natriuretic peptide: the Hoorn Study Endocr Connect 2012 Article

van Bussel BC, Henry RM, Schalkwijk CG, et al. Low-grade inflammation, but not endothelial dysfunction, is associated with greater carotid stiffness in the elderly: the Hoorn Study J Hypertens 2012 Article

van den Hurk K, Alssema M, Kamp O, et al. Independent associations of glucose status and arterial stiffness with left ventricular diastolic dysfunction: an 8-year follow-up of the Hoorn Study Diabetes Care 2012 Article

van Leeuwen N, Nijpels G, Becker ML, et al. A gene variant near ATM is significantly associated with metformin treatment response in type 2 diabetes: a replication and meta-analysis of five cohorts Diabetologia 2012 Article

van Raalte DH, van Leeuwen N, Simonis-Bik AM, et al. Glucocorticoid receptor gene polymorphisms are associated with reduced first-phase glucose-stimulated insulin secretion and disposition index in women, but not in men Diabet Med 2012 Article

Van Sijl AM, Van Den Hurk K, Peters MJL, et al. Different type of carotid arterial wall remodeling in rheumatoid arthritis compared with healthy subjects: A case-control study Journal of Rheumatology 2012 Article

van Vliet-Ostaptchouk JV, van Haeften TW, Landman GWD, et al. Common variants in the type 2 diabetes KCNQ1 gene are associated with impairments in insulin secretion during hyperglycaemic glucose clamp PLoS ONE 2012 Article

van’t Riet E, Schram MT, Abbink EJ, et al. The Diabetes Pearl: Diabetes biobanking in The Netherlands BMC Public Health 2012 Article

Welschen LM, Bot SD, Kostense PJ, et al. Effects of cardiovascular disease risk communication for patients with type 2 diabetes on risk perception in a randomized controlled trial: the @RISK study Diabetes Care 2012 Article

Wormser D, Di Angelantonio E, Kaptoge S, et al. Adult height and the risk of cause-specific death and vascular morbidity in 1 million people: Individual participant meta-analysis International Journal of Epidemiology 2012 Article

2011

Alssema M, Vistisen D, Heymans MW, et al. The Evaluation of Screening and Early Detection Strategies for Type 2 Diabetes and Impaired Glucose Tolerance (DETECT-2) update of the Finnish diabetes risk score for prediction of incident type 2 diabetes Diabetologia 2011 Article

Alssema M, Vistisen D, Heymans MW, et al. Risk scores for predicting type 2 diabetes: Using the optimal tool Diabetologia 2011 Article

Beijers HJ, Henry RM, Bravenboer B, et al. Metabolic syndrome in nondiabetic individuals associated with maladaptive carotid remodeling: the Hoorn Study Am J Hypertens 2011 Article

Brodovicz KG, Dekker JM, Rijkelijkhuizen JM, et al. The Finnish Diabetes Risk Score is associated with insulin resistance but not reduced β-cell function, by classical and model-based estimates Diabetic Medicine 2011 Article

Brodovicz KG, Girman CJ, Simonis-Bik AMC, et al. Postprandial metabolic responses to mixed versus liquid meal tests in healthy men and men with type 2 diabetes Diabetes Research and Clinical Practice 2011 Article

Claassen L, Henneman L, Nijpels G, et al. Causal beliefs and perceptions of risk for diabetes and cardiovascular disease, The Netherlands, 2007 Prev Chronic Dis 2011 Article

Dijkema MB, Mallant SF, Gehring U, et al. Long-term exposure to traffic-related air pollution and type 2 diabetes prevalence in a cross-sectional screening-study in the Netherlands Environ Health 2011 Article

Engelen L, Lund SS, Ferreira I, et al. Improved glycemic control induced by both metformin and repaglinide is associated with a reduction in blood levels of 3-deoxyglucosone in nonobese patients with type 2 diabetes European Journal of Endocrinology 2011 Article

Heringa SM, van den Berg E, Dekker JM, et al. Albuminuria and cognitive functioning in an older population: the Hoorn study Dement Geriatr Cogn Disord 2011 Article

Lakerveld J, Bot SD, Chinapaw MJ, et al. Measuring pathways towards a healthier lifestyle in the Hoorn Prevention Study: the Determinants of Lifestyle Behavior Questionnaire (DLBQ) Patient Educ Couns 2011 Article

Lamberts EJF, Nijpels G, Welschen LMC, et al. Long term patterns of use after initiation of oral antidiabetic drug therapy Pharmacoepidemiology and Drug Safety 2011 Article

Malanda UL, Bot SD, French DP, et al. Experience of hypoglycaemia is associated with changes in beliefs about diabetes in patients with type 2 diabetes Diabet Med 2011 Article

Reijmer YD, van den Berg E, Dekker JM, et al. The metabolic syndrome, atherosclerosis and cognitive functioning in a non-demented population: the Hoorn Study Atherosclerosis 2011 Article

Reijmer YD, van den Berg E, van Sonsbeek S, et al. Dementia risk score predicts cognitive impairment after a period of 15 years in a nondemented population Dement Geriatr Cogn Disord 2011 Article

Simonis-Bik AM, Boomsma DI, Dekker JM, et al. The heritability of beta cell function parameters in a mixed meal test design Diabetologia 2011 Article

van den Hurk K, Magliano DJ, Alssema M, et al. Type 2 diabetes strengthens the association between pulse pressure and chronic kidney disease: the AusDiab study J Hypertens 2011 Article

van den Hurk K, Reijmer YD, van den Berg E, et al. Heart failure and cognitive function in the general population: the Hoorn Study Eur J Heart Fail 2011 Article

van der Zwan LP, Scheffer PG, Dekker JM, et al. Systemic inflammation is linked to low arginine and high ADMA plasma levels resulting in an unfavourable NOS substrate-to-inhibitor ratio: the Hoorn Study Clin Sci (Lond) 2011 Article

Zavrelova H, Hoekstra T, Alssema M, et al. Progression and regression: distinct developmental patterns of diabetic retinopathy in patients with type 2 diabetes treated in the diabetes care system west-friesland, the Netherlands Diabetes Care 2011 Article

2010

Adhien P, Hugtenburg J, Van Dijk L, et al. Support by pharmacists for the therapy adherence of diabetes medication: A feasibility study British Journal of Clinical Pharmacology 2010 

Alssema M, El-Harchaoui K, Schindhelm RK, et al. Fasting cholesteryl ester transfer protein concentration is independently associated with the postprandial decrease in high-density lipoprotein cholesterol concentration after fat-rich meals: the Hoorn prandial study Metabolism 2010 Article

Beijers HJ, Ferreira I, Spronk HM, et al. Body composition as determinant of thrombin generation in plasma: the Hoorn study Arterioscler Thromb Vasc Biol 2010 Article

Bouwman V, Adriaanse MC, van ’t Riet E, et al. Depression, anxiety and glucose metabolism in the general dutch population: the new Hoorn study PLoS One 2010 Article

Engelen L, Ferreira I, Gaens KHJ, et al. The association between the-374T/A polymorphism of the receptor for advanced glycation endproducts gene and blood pressure and arterial stiffness is modified by glucose metabolism status: The Hoorn and CoDAM studies Journal of Hypertension 2010 Article

Heni M, Ketterer C, T Hart LM, et al. The impact of genetic variation in the G6PC2 gene on insulin secretion depends on glycemia Journal of Clinical Endocrinology and Metabolism 2010 Article

Lorenz MW, Bickel H, Bots ML, et al. Individual progression of carotid intima media thickness as a surrogate for vascular risk (PROG-IMT): Rationale and design of a meta-analysis project Am Heart J 2010 Article

Mattace-Raso FUS, Hofman A, Verwoert GC, et al. Determinants of pulse wave velocity in healthy people and in the presence of cardiovascular risk factors: ‘Establishing normal and reference values’ European Heart Journal 2010 Article

Peters MJL, Van Halm VP, Voskuyl AE, et al. Rheumatoid arthritis increases the risk of cardiovascular diseases as strongly as diabetes mellitus Nederlands Tijdschrift voor Geneeskunde 2010 

Pilz S, Henry RM, Snijder MB, et al. Vitamin D deficiency and myocardial structure and function in older men and women: the Hoorn study J Endocrinol Invest 2010 Article

Reiling E, Jafar-Mohammadi B, Van ‘T Riet E, et al. Genetic association analysis of LARS2 with type 2 diabetes Diabetologia 2010 Article

Reiling E, Ling C, Uitterlinden AG, et al. The association of mitochondrial content with prevalent and incident type 2 diabetes Journal of Clinical Endocrinology and Metabolism 2010 Article

Rijkelijkhuizen JM, McQuarrie K, Girman CJ, et al. Effects of meal size and composition on incretin, alpha-cell, and beta-cell responses Metabolism 2010 Article

Sarwar N, Sandhu MS, Ricketts SL, et al. Triglyceride-mediated pathways and coronary disease: Collaborative analysis of 101 studies The Lancet 2010 Article

Simonis-Bik AM, Nijpels G, van Haeften TW, et al. Gene variants in the novel type 2 diabetes loci CDC123/CAMK1D, THADA, ADAMTS9, BCL11A, and MTNR1B affect different aspects of pancreatic beta-cell function Diabetes 2010 Article

T Hart LM, Simonis-Bik AM, Nijpels G, et al. Combined risk allele score of eight type 2 diabetes genes is associated with reduced first-phase glucose-stimulated insulin secretion during hyperglycemic clamps Diabetes 2010 Article

van ’t Riet E, Alssema M, Rijkelijkhuizen JM, et al. Relationship between A1C and glucose levels in the general Dutch population: the new Hoorn study Diabetes Care 2010 Article

van den Berg E, Biessels GJ, Stehouwer CD, et al. Ten-year time course of risk factors for increased carotid intima-media thickness: the Hoorn Study Eur J Cardiovasc Prev Rehabil 2010 Article

van den Hurk K, Alssema M, Kamp O, et al. Slightly elevated B-type natriuretic peptide levels in a non-heart failure range indicate a worse left ventricular diastolic function in individuals with, as compared with individuals without, type 2 diabetes: the Hoorn Study Eur J Heart Fail 2010 Article

Van der Zwan LP, Scheffer PG, Dekker JM, et al. Hyperglycemia and oxidative stress strengthen the association between myeloperoxidase and blood pressure Hypertension 2010 Article

van der Zwan LP, Teerlink T, Dekker JM, et al. Plasma myeloperoxidase is inversely associated with endothelium-dependent vasodilation in elderly subjects with abnormal glucose metabolism Metabolism 2010 Article

Welschen LM, Bot SD, Dekker JM, et al. The @RISK Study: Risk communication for patients with type 2 diabetes: design of a randomised controlled trial BMC Public Health 2010 Article

Zhou XH, Qiao Q, Zethelius B, et al. Diabetes, prediabetes and cancer mortality Diabetologia 2010 Article

2009

Alssema M, Schindhelm RK, Rijkelijkhuizen JM, et al. Meal composition affects insulin secretion in women with type 2 diabetes: a comparison with healthy controls. The Hoorn prandial study Eur J Clin Nutr 2009 Article

Beijers HJ, Ferreira I, Bravenboer B, et al. Microalbuminuria and cardiovascular autonomic dysfunction are independently associated with cardiovascular mortality: evidence for distinct pathways: the Hoorn Study Diabetes Care 2009 Article

Bobbioni-Harsch E, Pataky Z, Makoundou V, et al. Fat distribution influences the cardio-metabolic profile in a clinically healthy European population European Journal of Clinical Investigation 2009 Article

de Rooij SR, Dekker JM, Kozakova M, et al. Fasting insulin has a stronger association with an adverse cardiometabolic risk profile than insulin resistance: the RISC study Eur J Endocrinol 2009 Article

de Rooij SR, Nijpels G, Nilsson PM, et al. Low-grade chronic inflammation in the relationship between insulin sensitivity and cardiovascular disease (RISC) population: associations with insulin resistance and cardiometabolic risk profile Diabetes Care 2009 Article

Engelen L, Ferreira I, Brouwers O, et al. Polymorphisms in glyoxalase 1 gene are not associated with vascular complications: the Hoorn and CoDAM studies J Hypertens 2009 Article

Gastaldelli A, Kozakova M, Höjlund K, et al. Fatty liver is associated with insulin resistance, risk of coronary heart disease, and early atherosclerosis in a large European population Hepatology 2009 Article

Henry RM, Ferreira I, Dekker JM, et al. The metabolic syndrome in elderly individuals is associated with greater muscular, but not elastic arterial stiffness, independent of low-grade inflammation, endothelial dysfunction or insulin resistance–The Hoorn Study J Hum Hypertens 2009 Article

Hyvärinen M, Qiao Q, Tuomilehto J, et al. Hyperglycemia and stroke mortality Diabetes Care 2009 Article

Jaakkola U, Kallio J, Heine RJ, et al. Neuropeptide Y polymorphism significantly magnifies diabetes and cardiovascular disease risk in obesity: the Hoorn Study Eur J Clin Nutr 2009 Article

Malanda UL, Bot SD, Kostense PJ, et al. Effects of self-monitoring of glucose in non-insulin treated patients with type 2 diabetes: design of the IN CONTROL-trial BMC Fam Pract 2009 Article

Muscelli E, Kozàkovà M, Flyvbjerg A, et al. The effect of menopause on carotid artery remodeling, insulin sensitivity, and plasma adiponectin in healthy women American Journal of Hypertension 2009 Article

Peters MJ, van Halm VP, Voskuyl AE, et al. Does rheumatoid arthritis equal diabetes mellitus as an independent risk factor for cardiovascular disease? A prospective study Arthritis Rheum 2009 Article

Pijl M, Timmermans DR, Claassen L, et al. Impact of communicating familial risk of diabetes on illness perceptions and self-reported behavioral outcomes: a randomized controlled trial Diabetes Care 2009 Article

Pilz S, Dobnig H, Nijpels G, et al. Vitamin D and mortality in older men and women Clin Endocrinol (Oxf) 2009 Article

Reiling E, van ’t Riet E, Groenewoud MJ, et al. Combined effects of single-nucleotide polymorphisms in GCK, GCKR, G6PC2 and MTNR1B on fasting plasma glucose and type 2 diabetes risk Diabetologia 2009 Article

Reiling E, van Vliet-Ostaptchouk JV, van ’t Riet E, et al. Genetic association analysis of 13 nuclear-encoded mitochondrial candidate genes with type II diabetes mellitus: the DAMAGE study Eur J Hum Genet 2009 Article

Rijkelijkhuizen JM, Doesburg T, Girman CJ, et al. Hepatic fat is not associated with beta-cell function or postprandial free fatty acid response Metabolism 2009 Article

Rijkelijkhuizen JM, Girman CJ, Mari A, et al. Classical and model-based estimates of beta-cell function during a mixed meal vs. an OGTT in a population-based cohort Diabetes Res Clin Pract 2009 Article

Roek MG, Welschen LM, Kostense PJ, et al. Web-based guided insulin self-titration in patients with type 2 diabetes: the Di@log study. Design of a cluster randomised controlled trial [TC1316] BMC Fam Pract 2009 Article

Schäfer SA, Tschritter O, MacHicao F, et al. Erratum: Impaired glucagon-like peptide-1-induced insulin secretion in carriers of transcription factor 7-like 2 (TCF7L2) gene polymorphisms Diabetologia 2009 Article

Snijder MB, Flyvbjerg A, Stehouwer CD, et al. Relationship of adiposity with arterial stiffness as mediated by adiponectin in older men and women: the Hoorn Study Eur J Endocrinol 2009 Article

van den Berg E, Dekker JM, Nijpels G, et al. Blood pressure levels in pre-diabetic stages are associated with worse cognitive functioning in patients with type 2 diabetes Diabetes Metab Res Rev 2009 Article

van der Heijden AA, Ortegon MM, Niessen LW, et al. Prediction of coronary heart disease risk in a general, pre-diabetic, and diabetic population during 10 years of follow-up: accuracy of the Framingham, SCORE, and UKPDS risk functions: The Hoorn Study Diabetes Care 2009 Article

van der Zwan LP, Teerlink T, Dekker JM, et al. Circulating oxidized LDL: determinants and association with brachial flow-mediated dilation J Lipid Res 2009 Article

van Halm VP, Peters MJ, Voskuyl AE, et al. Rheumatoid arthritis versus diabetes as a risk factor for cardiovascular disease: a cross-sectional study, the CARRE Investigation Ann Rheum Dis 2009 Article

Wedick NM, Snijder MB, Dekker JM, et al. Prospective investigation of metabolic characteristics in relation to weight gain in older adults: the Hoorn Study Obesity (Silver Spring) 2009 Article

Zhang L, Qiao Q, Tuomilehto J, et al. The impact of dyslipidaemia on cardiovascular mortality in individuals without a prior history of diabetes in the DECODE Study Atherosclerosis 2009 Article

2008

Adriaanse MC, Dekker JM, Heine RJ, et al. Symptoms of depression in people with impaired glucose metabolism or Type 2 diabetes mellitus: The Hoorn Study Diabet Med 2008 Article

Adriaanse MC, Pouwer F, Dekker JM, et al. Diabetes-related symptom distress in association with glucose metabolism and comorbidity: the Hoorn Study Diabetes Care 2008 Article

Adriaanse MC, Twisk JW, Dekker JM, et al. Perceptions of risk in adults with a low or high risk profile of developing type 2 diabetes; a cross-sectional population-based study Patient Educ Couns 2008 Article

Alssema M, Feskens EJ, Bakker SJ, et al. [Finnish questionnaire reasonably good predictor of the incidence of diabetes in The Netherlands] Ned Tijdschr Geneeskd 2008 Article

Alssema M, Schindhelm RK, Dekker JM, et al. Postprandial glucose and not triglyceride concentrations are associated with carotid intima media thickness in women with normal glucose metabolism: the Hoorn prandial study Atherosclerosis 2008 Article

Alssema M, Schindhelm RK, Dekker JM, et al. Determinants of postprandial triglyceride and glucose responses after two consecutive fat-rich or carbohydrate-rich meals in normoglycemic women and in women with type 2 diabetes mellitus: the Hoorn Prandial Study Metabolism 2008 Article

Boorsma W, Snijder MB, Nijpels G, et al. Body composition, insulin sensitivity, and cardiovascular disease profile in healthy Europeans Obesity (Silver Spring) 2008 Article

Brouwers MC, Dekker JM, van Greevenbroek MM, et al. Plasma triglycerides and LDL cholesterol are related in a parabolic fashion in the general population and patients with Type 2 diabetes mellitus: long-term follow-up results from the Hoorn study Diabet Med 2008 Article

Dekker JM, Funahashi T, Nijpels G, et al. Prognostic value of adiponectin for cardiovascular disease and mortality J Clin Endocrinol Metab 2008 Article

Du H, van der AD, van Bakel MM, van der Kallen CJ, et al. Glycemic index and glycemic load in relation to food and nutrient intake and metabolic risk factors in a Dutch population Am J Clin Nutr 2008 Article

Groenewoud MJ, Dekker JM, Fritsche A, et al. Variants of CDKAL1 and IGF2BP2 affect first-phase insulin secretion during hyperglycaemic clamps Diabetologia 2008 Article

Henry RM, Paulus WJ, Kamp O, et al. Deteriorating glucose tolerance status is associated with left ventricular dysfunction–the Hoorn Study Neth J Med 2008 Article

Hermans MM, Henry RM, Dekker JM, et al. Albuminuria, but not estimated glomerular filtration rate, is associated with maladaptive arterial remodeling: the Hoorn Study J Hypertens 2008 Article

Hoogeveen EK, Mackaay AJ, Beks PJ, et al. Evaluation of the one-minute exercise test to detect peripheral arterial disease Eur J Clin Invest 2008 Article

Kozakova M, Palombo C, Paterni M, et al. Body composition and common carotid artery remodeling in a healthy population Journal of Clinical Endocrinology and Metabolism 2008 Article

Lakerveld J, Bot SD, Chinapaw MJ, et al. Primary prevention of diabetes mellitus type 2 and cardiovascular diseases using a cognitive behavior program aimed at lifestyle changes in people at risk: Design of a randomized controlled trial BMC Endocr Disord 2008 Article

Nijpels G, Boorsma W, Dekker JM, et al. Absence of an acute insulin response predicts onset of type 2 diabetes in a Caucasian population with impaired glucose tolerance J Clin Endocrinol Metab 2008 Article

Nijpels G, Boorsma W, Dekker JM, et al. A study of the effects of acarbose on glucose metabolism in patients predisposed to developing diabetes: the Dutch acarbose intervention study in persons with impaired glucose tolerance (DAISI) Diabetes Metab Res Rev 2008 Article

Schäfer SA, Tschritter O, Machicao F, et al. Erratum: Impaired glucagon-like peptide-1-induced insulin secretion in carriers of transcription factor 7-like 2 (TCF7L2) gene polymorphisms (Diabetologia DOI: 10.1007/s00125-007-0753-6) Diabetologia 2008 Article

Scheffer PG, Teerlink T, Dekker JM, et al. Increased plasma apolipoprotein C-III concentration independently predicts cardiovascular mortality: the Hoorn Study Clin Chem 2008 Article

Schindhelm RK, Alssema M, Diamant M, et al. Comparison of two consecutive fat-rich and carbohydrate-rich meals on postprandial myeloperoxidase response in women with and without type 2 diabetes mellitus Metabolism 2008 Article

Snijder MB, van Dam RM, Stehouwer CD, et al. A prospective study of dairy consumption in relation to changes in metabolic risk factors: the Hoorn Study Obesity (Silver Spring) 2008 Article

van ’t Riet E, Alssema M, Nijpels G, et al. [Estimating the individual risk of diabetes: not on the grounds of overweight only] Ned Tijdschr Geneeskd 2008 Article

van den Berg E, Dekker JM, Nijpels G, et al. Cognitive functioning in elderly persons with type 2 diabetes and metabolic syndrome: the Hoorn study Dement Geriatr Cogn Disord 2008 Article

Van Hecke MV, Dekker JM, Nijpels G, et al. Homocysteine, S-adenosylmethionine and S-adenosylhomocysteine are associated with retinal microvascular abnormalities: the Hoorn Study Clin Sci (Lond) 2008 Article

Zhang L, Qiao Q, Tuomilehto J, et al. Blood lipid levels in relation to glucose status in European men and women without a prior history of diabetes: The DECODE Study Diabetes Research and Clinical Practice 2008 Article

2007

Alssema M, Dekker JM, Kuivenhoven JA, et al. Elevated cholesteryl ester transfer protein concentration is associated with an increased risk for cardiovascular disease in women, but not in men, with Type 2 diabetes: the Hoorn Study Diabet Med 2007 Article

Bos G, Poortvliet MC, Scheffer PG, et al. Dietary polyunsaturated fat intake is associated with low-density lipoprotein size, but not with susceptibility to oxidation in subjects with impaired glucose metabolism and type II diabetes: the Hoorn study Eur J Clin Nutr 2007 Article

de Mutsert R, Snijder MB, van der Sman-de Beer F, et al. Association between body mass index and mortality is similar in the hemodialysis population and the general population at high age and equal duration of follow-up J Am Soc Nephrol 2007 Article

Ferrannini E, Balkau B, Coppack SW, et al. Insulin resistance, insulin response, and obesity as indicators of metabolic risk Journal of Clinical Endocrinology and Metabolism 2007 Article

Hermans MM, Henry R, Dekker JM, et al. Estimated glomerular filtration rate and urinary albumin excretion are independently associated with greater arterial stiffness: the Hoorn Study J Am Soc Nephrol 2007 Article

Rijkelijkhuizen JM, Nijpels G, Heine RJ, et al. High risk of cardiovascular mortality in individuals with impaired fasting glucose is explained by conversion to diabetes: the Hoorn study Diabetes Care 2007 Article

Schäfer SA, Tschritter O, Machicao F, et al. Impaired glucagon-like peptide-1-induced insulin secretion in carriers of transcription factor 7-like 2 (TCF7L2) gene polymorphisms Diabetologia 2007 Article

Schindhelm RK, Alssema M, Scheffer PG, et al. Fasting and postprandial glycoxidative and lipoxidative stress are increased in women with type 2 diabetes Diabetes Care 2007 Article

Schindhelm RK, Dekker JM, Nijpels G, et al. Alanine aminotransferase predicts coronary heart disease events: a 10-year follow-up of the Hoorn Study Atherosclerosis 2007 Article

Schindhelm RK, Dekker JM, Nijpels G, et al. Alanine aminotransferase and the 6-year risk of the metabolic syndrome in Caucasian men and women: the Hoorn Study Diabet Med 2007 Article

Schindhelm RK, Diamant M, Heine RJ Nonalcoholic fatty liver disease and cardiovascular disease risk Curr Diab Rep 2007 

Schindhelm RK, Heine RJ, Diamant M Prevalence of nonalcoholic fatty liver disease and its association with cardiovascular disease among type 2 diabetic patients: Response to Targher et al. [2] Diabetes Care 2007 Article

Snijder MB, Dekker JM, Bouter LM, et al. Comment on: Schmidt MI, Duncan BB, Vigo a et al (2006) Leptin and incident type 2 diabetes: Risk or protection? Diabetologia 49:2086-2096 [10] Diabetologia 2007 Article

Snijder MB, Lips P, Seidell JC, et al. Vitamin D status and parathyroid hormone levels in relation to blood pressure: a population-based study in older men and women J Intern Med 2007 Article

Snijder MB, van der Heijden AA, van Dam RM, et al. Is higher dairy consumption associated with lower body weight and fewer metabolic disturbances? The Hoorn Study Am J Clin Nutr 2007 Article

Spijkerman AM, Gall MA, Tarnow L, et al. Endothelial dysfunction and low-grade inflammation and the progression of retinopathy in Type 2 diabetes Diabet Med 2007 Article

van Dam RM, Snijder MB, Dekker JM, et al. Potentially modifiable determinants of vitamin D status in an older population in the Netherlands: the Hoorn Study Am J Clin Nutr 2007 Article

Welschen LM, van Oppen P, Dekker JM, et al. The effectiveness of adding cognitive behavioural therapy aimed at changing lifestyle to managed diabetes care for patients with type 2 diabetes: design of a randomised controlled trial BMC Public Health 2007 Article

2006

Adriaanse MC, Dekker JM, Nijpels G, et al. Associations between depressive symptoms and insulin resistance: the Hoorn Study Diabetologia 2006 Article

de Jager J, Dekker JM, Kooy A, et al. Endothelial dysfunction and low-grade inflammation explain much of the excess cardiovascular mortality in individuals with type 2 diabetes: the Hoorn Study Arterioscler Thromb Vasc Biol 2006 Article

Henry RMA, Stehouwer CDA Structural and functional characteristics of circulation in diabetes mellitus type 2: Findings of the Hoorn study Hart Bulletin 2006 

Mukuddem-Petersen J, Snijder MB, van Dam RM, et al. Sagittal abdominal diameter: no advantage compared with other anthropometric measures as a correlate of components of the metabolic syndrome in elderly from the Hoorn Study Am J Clin Nutr 2006 Article

Schindhelm RK, Diamant M, Dekker JM, et al. Alanine aminotransferase as a marker of non-alcoholic fatty liver disease in relation to type 2 diabetes mellitus and cardiovascular disease Diabetes Metab Res Rev 2006 Article

Snijder MB, Heine RJ, Seidell JC, et al. Associations of adiponectin levels with incident impaired glucose metabolism and type 2 diabetes in older men and women: the hoorn study Diabetes Care 2006 Article

Stam F, van Guldener C, Becker A, et al. Endothelial dysfunction contributes to renal function-associated cardiovascular mortality in a population with mild renal insufficiency: the Hoorn study J Am Soc Nephrol 2006 Article

van Hecke MV, Dekker JM, Nijpels G, et al. Are retinal microvascular abnormalities associated with large artery endothelial dysfunction and intima-media thickness? The Hoorn Study Clin Sci (Lond) 2006 Article

Van Hove EC, Hansen T, Dekker JM, et al. The HADHSC gene encoding short-chain L-3-hydroxyacyl-CoA dehydrogenase (SCHAD) and type 2 diabetes susceptibility: The DAMAGE study Diabetes 2006 Article

Welschen LM, Nijpels G, Singh D Self-management programmes for older people may help reduce blood pressure. Commentary 1 Evid Based Cardiovasc Med 2006 Article

2005

Adriaanse MC, Dekker JM, Spijkerman AM, et al. Diabetes-related symptoms and negative mood in participants of a targeted population-screening program for type 2 diabetes: The Hoorn Screening Study Qual Life Res 2005 Article

Alssema M, Dekker JM, Nijpels G, et al. Proinsulin concentration is an independent predictor of all-cause and cardiovascular mortality: an 11-year follow-up of the Hoorn Study Diabetes Care 2005 Article

Bos G, Dekker JM, Feskens EJ, Ocke MC, et al. Interactions of dietary fat intake and the hepatic lipase -480C–>T polymorphism in determining hepatic lipase activity: the Hoorn Study Am J Clin Nutr 2005 Article 

Bos G, Snijder MB, Nijpels G, et al. Opposite contributions of trunk and leg fat mass with plasma lipase activities: the Hoorn study Obes Res 2005 Article

Dekker JM, Girman C, Rhodes T, et al. Metabolic syndrome and 10-year cardiovascular disease risk in the Hoorn Study Circulation 2005 Article

Ferraroni NR, Geloneze B, Mansour E, et al. Severe hypoleptinaemia associated with insulin resistance in patients with common variable immunodeficiency Clin Endocrinol (Oxf) 2005 Article

Girman CJ, Dekker JM, Rhodes T, et al. An exploratory analysis of criteria for the metabolic syndrome and its prediction of long-term cardiovascular outcomes: the Hoorn study Am J Epidemiol 2005 Article

Henry RM, Kamp O, Kostense PJ, et al. Mild renal insufficiency is associated with increased left ventricular mass in men, but not in women: an arterial stiffness-related phenomenon–the Hoorn Study Kidney Int 2005 Article

Qiao Q, Toumilehto J, Jousilahti P, et al. Comparison of three different definitions for the metabolic syndrome in non-diabetic Europeans British Journal of Diabetes and Vascular Disease 2005 Article

Scheffer PG, Teerlink T, Heine RJ Clinical significance of the physicochemical properties of LDL in type 2 diabetes Diabetologia 2005 Article

Schindhelm RK, Dekker JM, Nijpels G, et al. No independent association of alanine aminotransferase with risk of future type 2 diabetes in the Hoorn study Diabetes Care 2005 Article

Schindhelm RK, Diamant M, Bakker SJ, et al. Liver alanine aminotransferase, insulin resistance and endothelial dysfunction in normotriglyceridaemic subjects with type 2 diabetes mellitus Eur J Clin Invest 2005 Article

Snijder MB, van Dam RM, Visser M, et al. Adiposity in relation to vitamin D status and parathyroid hormone levels: a population-based study in older men and women J Clin Endocrinol Metab 2005 Article

Spijkerman AM, Smulders YM, Kostense PJ, et al. S-adenosylmethionine and 5-methyltetrahydrofolate are associated with endothelial function after controlling for confounding by homocysteine: the Hoorn Study Arterioscler Thromb Vasc Biol 2005 Article

Spoelstra-De Man AM, Smulders YM, Dekker JM, et al. Homocysteine levels are not associated with cardiovascular autonomic function in elderly Caucasian subjects without or with type 2 diabetes mellitus: the Hoorn Study J Intern Med 2005 Article

T Hart LM, Hansen T, Rietveld I, et al. Evidence that the mitochondrial leucyl tRNA synthetase (LARS2) gene represents a novel type 2 diabetes susceptibility gene Diabetes 2005 Article

van Hecke MV, Dekker JM, Nijpels G, et al. Inflammation and endothelial dysfunction are associated with retinopathy: the Hoorn Study Diabetologia 2005 Article

2004

Adriaanse MC, Dekker JM, Spijkerman AM, et al. Health-related quality of life in the first year following diagnosis of Type 2 diabetes: newly diagnosed patients in general practice compared with screening-detected patients. The Hoorn Screening Study Diabet Med 2004 Article

Adriaanse MC, Snoek FJ, Dekker JM, et al. No substantial psychological impact of the diagnosis of Type 2 diabetes following targeted population screening: The Hoorn Screening Study Diabet Med 2004 Article

Becker A, Henry RMA, Kostense PJ, et al. Erratum: Plasma homocysteine and S-adenosylmethionine in erythrocytes as determinants of carotid intima-media thickness: Different effects in diabetic and non-diabetic individuals The Hoorn Study (Atherosclerosis (2003) 169 (323-330)) Atherosclerosis 2004 Article

Bos G, Dekker JM, Heine RJ Non-HDL cholesterol contributes to the “hypertriglyceridemic waist” as a cardiovascular risk factor: the Hoorn study Diabetes Care 2004 Article

Bos G, Scheffer PG, Vieira D, et al. The relationship of lipoprotein lipase activity and LDL size is dependent on glucose metabolism in an elderly population: the Hoorn Study Diabetes Care 2004 Article

Henry RM, Ferreira I, Kostense PJ, et al. Type 2 diabetes is associated with impaired endothelium-dependent, flow-mediated dilation, but impaired glucose metabolism is not; The Hoorn Study Atherosclerosis 2004 Article

Henry RM, Kamp O, Kostense PJ, et al. Left ventricular mass increases with deteriorating glucose tolerance, especially in women: independence of increased arterial stiffness or decreased flow-mediated dilation: the Hoorn study Diabetes Care 2004 Article

Henry RM, Kostense PJ, Dekker JM, et al. Carotid arterial remodeling: a maladaptive phenomenon in type 2 diabetes but not in impaired glucose metabolism: the Hoorn study Stroke 2004 Article

Hills SA, Balkau B, Coppack SW, et al. The EGIR-RISC STUDY (The European group for the study of insulin resistance: relationship between insulin sensitivity and cardiovascular disease risk): I. Methodology and objectives Diabetologia 2004 Article

Maassen JA, T Hart LM, Van Essen E, et al. Mitochondrial Diabetes: Molecular Mechanisms and Clinical Presentation Diabetes 2004 Article

Qiao Q, Dekker JM, De Vegt F, et al. Two prospective studies found that elevated 2-hr glucose predicted male mortality independent of fasting glucose and HbA1c Journal of Clinical Epidemiology 2004 Article

Scheffer PG, Henry RM, Wever EJ, et al. LDL oxidative modifications in well- or moderately controlled type 2 diabetes Diabetes Metab Res Rev 2004 Article

Schram MT, Henry RM, van Dijk RA, et al. Increased central artery stiffness in impaired glucose metabolism and type 2 diabetes: the Hoorn Study Hypertension 2004 Article

Snijder MB, Dekker JM, Visser M, et al. Trunk fat and leg fat have independent and opposite associations with fasting and postload glucose levels: the Hoorn study Diabetes Care 2004 Article

Snijder MB, Henry RM, Visser M, et al. Regional body composition as a determinant of arterial stiffness in the elderly: The Hoorn Study J Hypertens 2004 Article

Spijkerman AM, Henry RM, Dekker JM, et al. Prevalence of macrovascular disease amongst type 2 diabetic patients detected by targeted screening and patients newly diagnosed in general practice: the Hoorn Screening Study J Intern Med 2004 Article

Stehouwer CD, Henry RM, Dekker JM, et al. Microalbuminuria is associated with impaired brachial artery, flow-mediated vasodilation in elderly individuals without and with diabetes: further evidence for a link between microalbuminuria and endothelial dysfunction–the Hoorn Study Kidney Int Suppl 2004 Article

Stumvoll M, Fritsche A, T’Hart LM, et al. The Gly482Ser variant in the peroxisome proliferator-activated receptor γ coactivator-1 is not associated with diabetes-related traits in non-diabetic German and Dutch populations Experimental and Clinical Endocrinology and Diabetes 2004 Article

T Hart LM, Fritsche A, Rietveld I, et al. Genetic Factors and Insulin Secretion: Gene Variants in the IGF Genes Diabetes 2004 Article

van Dam RM, Dekker JM, Nijpels G, et al. Coffee consumption and incidence of impaired fasting glucose, impaired glucose tolerance, and type 2 diabetes: the Hoorn Study Diabetologia 2004 Article

2003

Adriaanse MC, Snoek FJ, Dekker JM, et al. Perceived risk for Type 2 diabetes in participants in a stepwise population-screening programme Diabet Med 2003 Article

Becker A, Bos G, de Vegt F, et al. Cardiovascular events in type 2 diabetes: comparison with nondiabetic individuals without and with prior cardiovascular disease. 10-year follow-up of the Hoorn Study Eur Heart J 2003 Article

Becker A, Henry RM, Kostense PJ, et al. Plasma homocysteine and S-adenosylmethionine in erythrocytes as determinants of carotid intima-media thickness: different effects in diabetic and non-diabetic individuals. The Hoorn Study Atherosclerosis 2003 Article

Becker A, Kostense PJ, Bos G, et al. Hyperhomocysteinaemia is associated with coronary events in type 2 diabetes J Intern Med 2003 Article

Becker A, Smulders YM, Teerlink T, et al. S-adenosylhomocysteine and the ratio of S-adenosylmethionine to S-adenosylhomocysteine are not related to folate, cobalamin and vitamin B6 concentrations Eur J Clin Invest 2003 Article

Becker A, van der Does FE, van Hinsbergh VW, et al. Improvement of glycaemic control in type 2 diabetes: favourable changes in blood pressure, total cholesterol and triglycerides, but not in HDL cholesterol, fibrinogen, Von Willebrand factor and (pro)insulin Neth J Med 2003 Article

Bos G, Dekker JM, Nijpels G, et al. A combination of high concentrations of serum triglyceride and non-high-density-lipoprotein-cholesterol is a risk factor for cardiovascular disease in subjects with abnormal glucose metabolism–The Hoorn Study Diabetologia 2003 Article

De Vegt F, Dekker JM, Jager A, et al. Elevated fasting and postload glucose concentrations: Risk factors for developing type-2 diabetes mellitus; results of the Hoorn study Nederlands Tijdschrift voor Geneeskunde 2003 Article

Dekker JM, van der Kraan M, Nijpels G, et al. [Estimate of the number of new patients with type 2 diabetes mellitus in the Netherlands: at least 65,000 per year in the age group of 50 years and above] Ned Tijdschr Geneeskd 2003 Article

Gerritsen J, TenVoorde BJ, Dekker JM, et al. Measures of cardiovascular autonomic nervous function: agreement, reproducibility, and reference values in middle age and elderly subjects Diabetologia 2003 Article

Henry RM, Kostense PJ, Spijkerman AM, et al. Arterial stiffness increases with deteriorating glucose tolerance status: the Hoorn Study Circulation 2003 Article

Nijpels G, Serrée MJG, Dekker JM, et al. Self-monitoring in patients with type-2 diabetes mellitus one year after initiation of use: User errors in a quarter of cases Nederlands Tijdschrift voor Geneeskunde 2003 Article

Pouwer F, Beekman AT, Nijpels G, et al. Rates and risks for co-morbid depression in patients with Type 2 diabetes mellitus: results from a community-based study Diabetologia 2003 Article

Renders CM, Valk GD, de Sonnaville JJ, et al. Quality of care for patients with Type 2 diabetes mellitus–a long-term comparison of two quality improvement programmes in the Netherlands Diabet Med 2003 Article

Scheffer PG, Bos G, Volwater HG, et al. Associations of LDL size with in vitro oxidizability and plasma levels of in vivo oxidized LDL in Type 2 diabetic patients Diabet Med 2003 Article

Snijder MB, Dekker JM, Visser M, et al. Associations of hip and thigh circumferences independent of waist circumference with the incidence of type 2 diabetes: the Hoorn Study Am J Clin Nutr 2003 Article

Snijder MB, Dekker JM, Visser M, et al. Prospective relation of C-reactive protein with type 2 diabetes: Response to Han et al. [24] (multiple letters) Diabetes Care 2003 Article

Snijder MB, Dekker JM, Visser M, et al. Larger thigh and hip circumferences are associated with better glucose tolerance: the Hoorn study Obes Res 2003 Article

Spijkerman AM, Dekker JM, Nijpels G, et al. Microvascular complications at time of diagnosis of type 2 diabetes are similar among diabetic patients detected by targeted screening and patients newly diagnosed in general practice: the hoorn screening study Diabetes Care 2003 Article

T Hart LM, Maassen JA, Dekker JM, et al. Lack of association between gene variants in the ALMS1 gene and Type 2 diabetes mellitus [3] Diabetologia 2003 Article

van Dijk RA, Bakker SJ, Scheffer PG, et al. Associations of metabolic variables with arterial stiffness in type 2 diabetes mellitus: focus on insulin sensitivity and postprandial triglyceridaemia Eur J Clin Invest 2003 Article

van Leiden HA, Dekker JM, Moll AC, et al. Risk factors for incident retinopathy in a diabetic and nondiabetic population: the Hoorn study Arch Ophthalmol 2003 Article

2002

Adriaanse M, Snoek F, Dekker J, et al. Screening for Type 2 diabetes: an exploration of subjects’ perceptions regarding diagnosis and procedure Diabet Med 2002 Article

Becker A, van Hinsbergh VW, Jager A, et al. Why is soluble intercellular adhesion molecule-1 related to cardiovascular mortality? Eur J Clin Invest 2002 Article

de Vegt F, Dekker JM, Groeneveld WJ, et al. Moderate alcohol consumption is associated with lower risk for incident diabetes and mortality: the Hoorn Study Diabetes Res Clin Pract 2002 Article

Henry RM, Kostense PJ, Bos G, et al. Mild renal insufficiency is associated with increased cardiovascular mortality: The Hoorn Study Kidney Int 2002 Article

Jager A, van Hinsbergh VW, Kostense PJ, et al. C-reactive protein and soluble vascular cell adhesion molecule-1 are associated with elevated urinary albumin excretion but do not explain its link with cardiovascular risk Arterioscler Thromb Vasc Biol 2002 Article

Schram MT, Kostense PJ, Van Dijk RA, et al. Diabetes, pulse pressure and cardiovascular mortality: the Hoorn Study J Hypertens 2002 Article

Spijkerman A, Griffin S, Dekker J, et al. What is the risk of mortality for people who are screen positive in a diabetes screening programme but who do not have diabetes on biochemical testing? Diabetes screening programmes from a public health perspective J Med Screen 2002 Article

Spijkerman AM, Adriaanse MC, Dekker JM, et al. Diabetic patients detected by population-based stepwise screening already have a diabetic cardiovascular risk profile Diabetes Care 2002 Article

Spijkerman AM, Dekker JM, Nijpels G, et al. Impact of diabetes duration and cardiovascular risk factors on mortality in type 2 diabetes: the Hoorn Study Eur J Clin Invest 2002 Article

Stehouwer CD, Gall MA, Twisk JW, et al. Increased urinary albumin excretion, endothelial dysfunction, and chronic low-grade inflammation in type 2 diabetes: progressive, interrelated, and independently associated with risk of death Diabetes 2002 Article

T Hart LM, Nijpels G, Dekker JM, et al. Variations in insulin secretion in carriers of gene variants in IRS-1 and -2 Diabetes 2002 Article

t Hart LM, Van Haeften TW, Dekker JM, et al. Variations in insulin secretion in carriers of the E23K variant in the KIR6.2 Subunit of the ATP-sensitive K+ channel in the β-cell Diabetes 2002 Article

Van De Poll-Franse LV, Valk GD, Renders CM, et al. Longitudinal assessment of the development of diabetic polyneuropathy and associated risk factors Diabetic Medicine 2002 Article

van Dijk RA, van Ittersum FJ, Westerhof N, et al. Determinants of brachial artery mean 24 h pulse pressure in individuals with Type II diabetes mellitus and untreated mild hypertension Clin Sci (Lond) 2002 Article

van Leiden HA, Dekker JM, Moll AC, et al. Blood pressure, lipids, and obesity are associated with retinopathy: the hoorn study Diabetes Care 2002 Article

2001

de Vegt F, Dekker JM, Jager A, et al. Relation of impaired fasting and postload glucose with incident type 2 diabetes in a Dutch population: The Hoorn Study Jama 2001 Article

Gerritsen J, Dekker JM, TenVoorde BJ, et al. Impaired autonomic function is associated with increased mortality, especially in subjects with diabetes, hypertension, or a history of cardiovascular disease: the Hoorn Study Diabetes Care 2001 Article

Jager A, Kostense PJ, Nijpels G, et al. Serum homocysteine levels are associated with the development of (micro)albuminuria: the Hoorn study Arterioscler Thromb Vasc Biol 2001 Article

Jager A, van Hinsbergh VW, Kostense PJ, et al. Prognostic implications of retinopathy and a high plasma von Willebrand factor concentration in type 2 diabetic subjects with microalbuminuria Nephrol Dial Transplant 2001 Article

Spoelstra-de Man AM, Brouwer CB, Stehouwer CD, et al. Rapid progression of albumin excretion is an independent predictor of cardiovascular mortality in patients with type 2 diabetes and microalbuminuria Diabetes Care 2001 Article

van Dijk RA, Dekker JM, Nijpels G, et al. Brachial artery pulse pressure and common carotid artery diameter: mutually independent associations with mortality in subjects with a recent history of impaired glucose tolerance Eur J Clin Invest 2001 Article

2000

Becker A, Van Hinsbergh VW, Kostense PJ, et al. Serum homocysteine is weakly associated with von Willebrand factor and soluble vascular cell adhesion molecule 1, but not with C-reactive protein in type 2 diabetic and non-diabetic subjects – The Hoorn Study Eur J Clin Invest 2000 Article

de Vegt F, Dekker JM, Stehouwer CD, et al. Similar 9-year mortality risks and reproducibility for the World Health Organization and American Diabetes Association glucose tolerance categories: the Hoorn Study Diabetes Care 2000 Article

Gerritsen J, Dekker JM, TenVoorde BJ, et al. Glucose tolerance and other determinants of cardiovascular autonomic function: the Hoorn Study Diabetologia 2000 Article

Gerritsen J, TenVoorde BJ, Dekker JM, et al. Baroreflex sensitivity in the elderly: influence of age, breathing and spectral methods Clin Sci (Lond) 2000 Article

Hoogeveen EK, Kostense PJ, Eysink PE, et al. Hyperhomocysteinemia is associated with the presence of retinopathy in type 2 diabetes mellitus: the Hoorn study Arch Intern Med 2000 Article

Hoogeveen EK, Kostense PJ, Jakobs C, et al. Hyperhomocysteinemia increases risk of death, especially in type 2 diabetes : 5-year follow-up of the Hoorn Study Circulation 2000 Article

Hoogeveen EK, Kostense PJ, Jakobs C, et al. Hyperhomocysteinaemia is not associated with isolated crural arterial occlusive disease: The Hoorn Study J Intern Med 2000 Article

Jager A, van Hinsbergh VW, Kostense PJ, et al. Increased levels of soluble vascular cell adhesion molecule 1 are associated with risk of cardiovascular mortality in type 2 diabetes: the Hoorn study Diabetes 2000 Article

Mooy JM, de Vries H, Grootenhuis PA, et al. Major stressful life events in relation to prevalence of undetected type 2 diabetes: the Hoorn Study Diabetes Care 2000 Article

Pereira Arias AM, Romijn JA, Corssmit EP, et al. Indomethacin decreases insulin secretion in patients with type 2 diabetes mellitus Metabolism 2000 Article

Smulders YM, Jager A, Gerritsen J, et al. Cardiovascular autonomic function is associated with (micro-)albuminuria in elderly Caucasian sujects with impaired glucose tolerance or type 2 diabetes: the Hoorn Study Diabetes Care 2000 Article

T Hart LM, Dekker JM, Van Haeften TW, et al. Reduced second phase insulin secretion in carriers of a sulphonylurea receptor gene variant associating with Type II diabetes mellitus Diabetologia 2000 Article

van Dijk RA, Nijpels G, Twisk JW, et al. Change in common carotid artery diameter, distensibility and compliance in subjects with a recent history of impaired glucose tolerance: a 3-year follow-up study J Hypertens 2000 Article

1999

A Paw MJMC, Dekker JM, Feskens EJM, et al. How to select a frail elderly population? A comparison of three working definitions Journal of Clinical Epidemiology 1999 Article

Baan CA, Ruige JB, Stolk RP, Witteman JC, et al. Performance of a predictive model to identify undiagnosed diabetes in a health care setting Diabetes Care 1999 Article

Bouma M, Dekker JH, de Sonnaville JJ, et al. How valid is fasting plasma glucose as a parameter of glycemic control in non-insulin-using patients with type 2 diabetes? Diabetes Care 1999 Article

Bouma M, Dekker JH, van Eijk JT, et al. Metabolic control and morbidity of type 2 diabetic patients in a general practice network Fam Pract 1999 Article

de Vegt F, Dekker JM, Ruhé HG, et al. Hyperglycaemia is associated with all-cause and cardiovascular mortality in the Hoorn population: the Hoorn Study Diabetologia 1999 Article

Hart LM, Stolk RP, Dekker JM, et al. Prevalence of variants in candidate genes for type 2 diabetes mellitus in The Netherlands: the Rotterdam study and the Hoorn study J Clin Endocrinol Metab 1999 Article

Hoogeveen EK, Kostense PJ, Valk GD, et al. Hyperhomocysteinaemia is not related to risk of distal somatic polyneuropathy: the Hoorn Study J Intern Med 1999 Article

Jager A, Kostense PJ, Ruhé HG, et al. Microalbuminuria and peripheral arterial disease are independent predictors of cardiovascular and all-cause mortality, especially among hypertensive subjects: five-year follow-up of the Hoorn Study Arterioscler Thromb Vasc Biol 1999 Article

Jager A, van Hinsbergh VW, Kostense PJ, et al. von Willebrand factor, C-reactive protein, and 5-year mortality in diabetic and nondiabetic subjects: the Hoorn Study Arterioscler Thromb Vasc Biol 1999 Article

Ruige JB, Dekker JM, Blum WF, et al. Leptin and variables of body adiposity, energy balance, and insulin resistance in a population-based study. The Hoorn Study Diabetes Care 1999 Article

Ruige JB, Dekker JM, Nijpels G, et al. Hyperproinsulinaemia in impaired glucose tolerance is associated with a delayed insulin response to glucose Diabetologia 1999 Article

T Hart LM, De Knijff P, Dekker JM, et al. Variants in the sulphonylurea receptor gene: Association of the exon 16- 3t variant with Type II diabetes mellitus in Dutch Caucasians Diabetologia 1999 Article

1998 

Bakker SJ, Hoogeveen EK, Nijpels G, et al. The association of dietary fibres with glucose tolerance is partly explained by concomitant intake of thiamine: the Hoorn Study Diabetologia 1998 Article

de Vegt F, Dekker JM, Stehouwer CD, et al. The 1997 American Diabetes Association criteria versus the 1985 World Health Organization criteria for the diagnosis of abnormal glucose tolerance: poor agreement in the Hoorn Study Diabetes Care 1998 Article

Grootenhuis PA, Mooy JM, Kostense PJ, et al. Dissimilar association of conventional immuno-reactive versus specific insulin with cardiovascular risk factors: a consequence of proinsulinaemia? Diabetes Res Clin Pract 1998 Article

Hoogeveen EK, Kostense PJ, Beks PJ, et al. Hyperhomocysteinemia is associated with an increased risk of cardiovascular disease, especially in non-insulin-dependent diabetes mellitus: a population-based study Arterioscler Thromb Vasc Biol 1998 Article

Hoogeveen EK, Kostense PJ, Jager A, et al. Serum homocysteine level and protein intake are related to risk of microalbuminuria: the Hoorn Study Kidney Int 1998 Article

Jager A, Kostense PJ, Nijpels G, et al. Microalbuminuria is strongly associated with NIDDM and hypertension, but not with the insulin resistance syndrome: the Hoorn Study Diabetologia 1998 Article

Karvonen MK, Pesonen U, Koulu M, et al. Association of a leucine(7)-to-proline(7) polymorphism in the signal peptide of neuropeptide Y with high serum cholesterol and LDL cholesterol levels Nature Medicine 1998 Article

Mooy JM, Grootenhuis PA, de Vries H, et al. Determinants of specific serum insulin concentrations in a general Caucasian population aged 50 to 74 years (the Hoorn Study) Diabet Med 1998 Article

Nijpels G Determinants for the progression from impaired glucose tolerance to non-insulin-dependent diabetes mellitus Eur J Clin Invest 1998 Article

Stolk RP, De Vegt F, Heine RJ The consequences of new American guidelines for the diagnosis of diabetes mellitus in the Netherlands Nederlands Tijdschrift voor Geneeskunde 1998 Article

van der Does FE, de Neeling JN, Snoek FJ, et al. Randomized study of two different target levels of glycemic control within the acceptable range in type 2 diabetes. Effects on well-being at 1 year Diabetes Care 1998 Article

1997

Beks PH, Mackaay AJ, de Vries H, et al. Carotid artery stenosis is related to blood glucose level in an elderly Caucasian population: the Hoorn Study Diabetologia 1997 Article

Hoogeveen EK, Kostense PJ, Jakobs C, et al. Does metformin increase the serum total homocysteine level in non-insulin-dependent diabetes mellitus? J Intern Med 1997 Article

Nijpels G, Popp-Snijders C, Kostense PJ, et al. Cardiovascular risk factors prior to the development of non-insulin-dependent diabetes mellitus in persons with impaired glucose tolerance: the Hoorn Study J Clin Epidemiol 1997 Article

Ruige JB, Batstra MR, Aanstoot HJ, et al. Low prevalence of antibodies to GAD65 in a 50- to 74-year-old general Dutch population. The Hoorn Study Diabetes Care 1997 Article

Ruige JB, de Neeling JN, Kostense PJ, et al. Performance of an NIDDM screening questionnaire based on symptoms and risk factors Diabetes Care 1997 Article

1996

Blonk MC, Jacobs MAJM, Biesheuvel EHE, et al. Determinants of glucose and lipid oxidation rates, and of glucose storage in Type II diabetes mellitus Diabetes, Nutrition and Metabolism – Clinical and Experimental 1996

de Neeling JN, Beks PJ, Bertelsmann FW, et al. Peripheral somatic nerve function in relation to glucose tolerance in an elderly Caucasian population: the Hoorn study Diabet Med 1996 Article

Heine RJ, Nijpels G, Mooy JM New data on the rate of progression of impaired glucose tolerance to NIDDM and predicting factors Diabet Med 1996 Article

Mooy JM, Grootenhuis PA, de Vries H, et al. Intra-individual variation of glucose, specific insulin and proinsulin concentrations measured by two oral glucose tolerance tests in a general Caucasian population: the Hoorn Study Diabetologia 1996 Article

Nijpels G, Popp-Snijders C, Kostense PJ, et al. Fasting proinsulin and 2-h post-load glucose levels predict the conversion to NIDDM in subjects with impaired glucose tolerance: the Hoorn Study Diabetologia 1996 Article

Van der Does FE, De Neeling JN, Snoek FJ, et al. Symptoms and well-being in relation to glycemic control in type II diabetes Diabetes Care 1996 Article

1995

Beks PJ, Mackaay AJ, de Neeling JN, et al. Peripheral arterial disease in relation to glycaemic level in an elderly Caucasian population: the Hoorn study Diabetologia 1995 Article

Mackaay AJ, Beks PJ, Dur AH, Bischoff M, et al. The distribution of peripheral vascular disease in a Dutch Caucasian population: comparison of type II diabetic and non-diabetic subjects Eur J Vasc Endovasc Surg 1995 Article

Mackaay AJC, Beks PJ, Dur AHM, et al. Is toe pressure a better parameter of peripheral vascular integrity than ankle pressure? Comparison of diabetic with nondiabetic subjects in Dutch epidemiological study Journal of Vascular Technology 1995 Article

Mooy JM, Grootenhuis PA, de Vries H, et al. Prevalence and determinants of glucose intolerance in a Dutch caucasian population. The Hoorn Study Diabetes Care 1995 Article

1994

Blonk MC, Jacobs MA, Friedberg CE, et al. Determinants of insulin sensitivity and consequences for lipoproteins and blood pressure in subjects with non-insulin-dependent diabetes mellitus Metabolism 1994 Article

Grootenhuis PA, Snoek FJ, Heine RJ, et al. Development of a type 2 diabetes symptom checklist: a measure of symptom severity Diabet Med 1994 Article

Nijpels G, van der Wal PS, Bouter LM, et al. Comparison of three methods for the quantification of beta-cell function and insulin sensitivity Diabetes Res Clin Pract 1994 Article

1993

Gans RO, Stehouwer CD, Bilo HJ, et al.  Effect of cilazapril on glucose tolerance and lipid profile in hypertensive patients with non-insulin-dependent diabetes mellitus Neth J Med 1993 Article

1991

Gans RO, Bilo HJ, von Maarschalkerweerd WW, et al.  Exogenous insulin augments in healthy volunteers the cardiovascular reactivity to noradrenaline but not to angiotensin II J Clin Invest 1991 Article

Toorn L, Bilo HJ, et al.  Renal and cardiovascular effects of exogenous insulin in healthy volunteers Clin Sci (Lond) 1991 Article

1990

Heine RJ, Tuynman H, Van Der Veen EA  The effects on insulin dynamics of mixing human phosphate buffered regular insulin with human lente insulin Diabetes, Nutrition and Metabolism – Clinical and Experimental 1990 

1989

Heine RJ, Mulder C, Popp-Snijders C, et al. Linoleic-acid-enriched diet: long-term effects on serum lipoprotein and apolipoprotein concentrations and insulin sensitivity in noninsulin-dependent diabetic patients Am J Clin Nutr 1989 Article

Heine RJ, van der Heyden EA, van der Veen EA Responses to human and porcine insulin in healthy subjects Lancet 1989 Article

1987

Heine RJ, Van Der Stap H, Salemink PJM  Pharmacokinetics and miscibility of 4 highly purified porcine insulins: A study in vitro and in healthy volunteers Diabetes Research 1987 Article

1986

Heine RJ, Sikkenk AC, Eizenga WH, et al.  Delayed onset of action of soluble insulin after premixing with U100 lente insulin Diabetes Research and Clinical Practice 1986 Article

1985

Heine RJ, Sikkenk AC, Bilo HJG  Comparison of two commonly used insulin injection techniques Diabetic Medicine 1 Article

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